SCT Annual Meeting Presentations & Videos

Discover SCT's Scientific Knowledge-Bank

  693 Learning Opportunities Found

J. Michael Gaziano
2017 (Liverpool) Annual Meeting
Founders Lecture
The Million Veteran Program: A Modern Mega-Cohort within a Healthcare system Using Big Health Data to Improve Health Care
Jerry Wolinsky
2017 (Liverpool) Annual Meeting
Trial of the Year Award
ORATORIO
James J. Dignam
2017 (Liverpool) Annual Meeting
Award Presentation
Thomas C. Chalmers Scholarship and Sylvan Green Awards
Susan S. Ellenberg
2017 (Liverpool) Annual Meeting
Curtis Meinert Lecture
Clinical Trials in the Twenty-First Century: Ongoing Challenges and Emerging Issues
Will Meurer & Jon Nichols
2017 (Liverpool) Annual Meeting
Special Presentation
Opening Remarks, Program Scientific Committee Co-Chairs
Susan Halabi
2017 (Liverpool) Annual Meeting
Fellows Presentation
Presentation of the Class of 2017 Fellows
Siobhan Bourke
2017 (Liverpool) Annual Meeting
Contributed Session
Rituximab for the treatment of neuromyelitis optica: an application of individual patient data meta-analysis in a rare disease.
Clare Clement
2017 (Liverpool) Annual Meeting
Contributed Session
"To have and to hold, from this day forward": Understanding current practice regarding retention of trial particpants
Clare Clement
2017 (Liverpool) Annual Meeting
Contributed Session
‘Enquiry into how Qualitative Methods Influence Trials and their Yields’ (EQUITY): Exploring registered trials that include a reported qualitative component
Loretta Davies
2017 (Liverpool) Annual Meeting
Contributed Session
“I struggle with equipoise”: a qualitative study exploring clinicians’ views of a randomised controlled trial (ACL SNNAP) prior to trial conduct
Andrew Embleton
2017 (Liverpool) Annual Meeting
Contributed Session
“If a tree falls in a forest…”: Abstract view statistics as a measure of research impact
Heather Morgan
2017 (Liverpool) Annual Meeting
Contributed Session
“Is that it?” – using ‘Explorachoc’ to engage the public with clinical trials and health services research
Alex Nicolson
2017 (Liverpool) Annual Meeting
Contributed Session
“More than the Emperor’s new clothes”: Enhancing meaningful Patient and Public Involvement in Trial Oversight Committees through qualitative research with eight clinical trials facing challenges
Mary Rauchenberger
2017 (Liverpool) Annual Meeting
Contributed Session
“Will you walk a little faster?” - Joining the database development dance
Laura Pankhurst
2017 (Liverpool) Annual Meeting
Contributed Session
40 is the magic number
Alexina Mason
2017 (Liverpool) Annual Meeting
Contributed Session
A Bayesian framework to address missing not at random data in longitudinal studies with multiple types of missingness
Moreno Ursino
2017 (Liverpool) Annual Meeting
Contributed Session
A Bayesian weighted quasi-likelihood design for Phase I/II clinical trial with repeated dose administration in preterm newborns.
Alba Realpe
2017 (Liverpool) Annual Meeting
Contributed Session
A case study method to support and promote recruitment at a multi-centre RCT comparing surgical versus non-surgical treatments
Joy Esterlitz
2017 (Liverpool) Annual Meeting
Contributed Session
A Common Data Language for Clinical Research Studies: Five (5) New Disease Recommendations from the National Institute of Neurological Disorders and Stroke, National Institutes of Health Common Data Elements Project
Brennan Kahan
2017 (Liverpool) Annual Meeting
Contributed Session
A comparison of adjudication approaches for clinical trials
Lesley-Anne Carter
2017 (Liverpool) Annual Meeting
Contributed Session
A comparison of baseline as response and missing indicator methods for missing baseline data in a mixed design cluster randomised control trial
Jemma Hudson
2017 (Liverpool) Annual Meeting
Contributed Session
A comparison of methods to handle missing data in the analysis of an area under the curve outcome
Ines Rombach
2017 (Liverpool) Annual Meeting
Contributed Session
A comparison of statistical approaches for analysing missing longitudinal patient reported outcome data in randomised controlled trials
Peter Godolphin
2017 (Liverpool) Annual Meeting
Contributed Session
A comparison of stroke diagnosis at trial entry by local clinicians versus independent adjudicators: secondary analysis and simulation
Marcus Johnson
2017 (Liverpool) Annual Meeting
Contributed Session
A Cross-Cutting Approach to Clinical Trial Success: The US Department of Veterans Affairs’ Network of Dedicated Enrollment Sites (NODES) Model
Suzanne Freeman
2017 (Liverpool) Annual Meeting
Contributed Session
A framework for identifying treatment-covariate interactions in individual participant data network meta-analysis
Gordon Fernie
2017 (Liverpool) Annual Meeting
Contributed Session
A good use of time and money? A study of how trial data collection effort is distributed across different categories of data.
Toby Prevost
2017 (Liverpool) Annual Meeting
Contributed Session
A journey from statistical consultation to funded adaptive trial
Iryna Schlackow
2017 (Liverpool) Annual Meeting
Contributed Session
A lifetime disease model based on an RCT: development, validation and applications
Pankaj Mistry
2017 (Liverpool) Annual Meeting
Contributed Session
A literature review of the use of Adaptive Design methods in Oncology trials.
Derk Arts
2017 (Liverpool) Annual Meeting
Contributed Session
A look at the future of data standardization and sharing in clinical research.
Graham Wheeler
2017 (Liverpool) Annual Meeting
Contributed Session
A model-free Bayesian adaptive design for combination therapy dose-finding trials with censored time-to-toxicity data
Claire Dyer
2017 (Liverpool) Annual Meeting
Contributed Session
A Multi-Centred Study Validating a Bleeding Assessment Tool (BAT) Developed by the Biomedical Excellence for Safer Transfusion (BEST) Collaborative For Use in Adult Patients with Haematological Malignancy
Matteo Quartagno
2017 (Liverpool) Annual Meeting
Contributed Session
A new design for trials for finding optimal treatment duration
Emma Wang
2017 (Liverpool) Annual Meeting
Contributed Session
A novel approach to analysis of clinical trials for rare cancers assuming symmetry
Hannah Buckley
2017 (Liverpool) Annual Meeting
Contributed Session
A Phase II randomised controlled trial with biomarkers in soft tissue sarcoma: application of a biomarker stratified design
Elizabeth Randell
2017 (Liverpool) Annual Meeting
Contributed Session
A pilot randomised controlled trial of community led anti-psychotic drug reduction for adults with learning disabilities: ANDREA-LD
Meng Liu
2017 (Liverpool) Annual Meeting
Contributed Session
A predictive probability interim design for phase II clinical trials with continuous endpoints
Toshimitsu Hamasaki
2017 (Liverpool) Annual Meeting
Contributed Session
A Program for Training the Next Generation of Biostatisticians in Japan: Developing On-the-Job Training at NCVC
Caitlin O'Hara
2017 (Liverpool) Annual Meeting
Contributed Session
A qualitative feasibility study to inform fluids in shock (FiSh) - a pilot randomised controlled trial of fluid bolus therapy in septic shock
Caroline Rick
2017 (Liverpool) Annual Meeting
Contributed Session
A reflection on the management of a trial of speech and language therapy.
James Howlett
2017 (Liverpool) Annual Meeting
Contributed Session
A Response-Adaptive Trial to Determine the Optimal IL-2 Dose-Frequency to Achieve Multiple Target Increases on Regulatory T Cells in Type 1 Diabetes: DILfrequency study
Isabelle Smith
2017 (Liverpool) Annual Meeting
Contributed Session
A review of design and analysis methods for pressure ulcer research
Daniel Greenwood
2017 (Liverpool) Annual Meeting
Contributed Session
A review of dose escalation methods in first-in-human small molecule oncology clinical trials
Dewen Yang
2017 (Liverpool) Annual Meeting
Contributed Session
A Review of the Essentials and Pitfalls of the Lugano Classification in Malignant Lymphoma Trials
Jelena Savovic
2017 (Liverpool) Annual Meeting
Contributed Session
A revised tool for assessing risk of bias in randomized trials (RoB 2.0)
Andrew Forbes
2017 (Liverpool) Annual Meeting
Contributed Session
A simple relationship between power and expected confidence interval width
Diane Whitham
2017 (Liverpool) Annual Meeting
Contributed Session
A study aimed at improving the conduct and efficiency of trials by developing a standardised set of site performance metrics and a systematic approach to reporting
Sophie Betteridge
2017 (Liverpool) Annual Meeting
Contributed Session
A system for real-time integration of laboratory data into trials of targeted therapy with applications to Acute Myeloid Leukaemia
Rebecca Barnes
2017 (Liverpool) Annual Meeting
Contributed Session
A systematic mapping review of methods used for the evaluation of implementation fidelity in primary care trials
Sena Jawad
2017 (Liverpool) Annual Meeting
Contributed Session
A systematic review identifying neonatal core data elements for clinical trials, and assessment of data completeness of identified data elements using the National Neonatal Research Database (NNRD)
Richéal Burns
2017 (Liverpool) Annual Meeting
Contributed Session
A systematic review of analytical methods applied for discarded organs in kidney and liver transplantation research
Heather Catt
2017 (Liverpool) Annual Meeting
Contributed Session
A systematic review of core outcomes for Crohn's Disease in adults
Katie Gillies
2017 (Liverpool) Annual Meeting
Contributed Session
A systematic review of measures of informed consent for randomised controlled trials.
Katie Sworn
2017 (Liverpool) Annual Meeting
Contributed Session
A systematic review of the different approaches to intervention development
Jane Dennis
2017 (Liverpool) Annual Meeting
Contributed Session
A systematic review to inform a trial of comprehensive pain management for patients with chronic pain after total knee replacement: the STAR experience
Jamie Kirkham
2017 (Liverpool) Annual Meeting
Contributed Session
A systematic search of ClinicalTrials.gov to assess the uptake of core outcome sets
Allan Walker
2017 (Liverpool) Annual Meeting
Contributed Session
A targeted approach to drug-supply in RCTs limits wastage and can reduce costs. The experience of the MS-Smart trial
Heather Bagley
2017 (Liverpool) Annual Meeting
Contributed Session
A Toolkit for Patient and Public Involvement in a Clinical Trials Unit – An Update & Next Steps
Michelle DeVeaux
2017 (Liverpool) Annual Meeting
Contributed Session
A Two-Stage, Phase II Clinical Trial Design with Nested Criteria for Early Stopping and Efficacy
Chao Huang
2017 (Liverpool) Annual Meeting
Contributed Session
A validation and calibration process on self-reported tobacco with participants’ cotinine levels in Building Blocks
Nigel Stallard
2017 (Liverpool) Annual Meeting
Contributed Session
A Value of Information approach to optimal design of confirmatory clinical trials
Joana Vasconcelos
2017 (Liverpool) Annual Meeting
Contributed Session
A way to assess the impact of an omitted study on the overall meta-analysis estimate
Sheau-Chiann Chen
2017 (Liverpool) Annual Meeting
Contributed Session
A web application for optimal selection of adaptive designs in phase I oncology clinical trials
Kevin Wilson
2017 (Liverpool) Annual Meeting
Contributed Session
A WEB-BASED SYSTEM FOR THE MANAGEMENT AND STORAGE OF METADATA FOR MULTI-CENTER CLINICAL TRIALS
Jane Aziz
2017 (Liverpool) Annual Meeting
Contributed Session
Access and security considerations of using ePROMS to collect follow-up data for clinical trials
Rema Raman, PhD
2017 (Liverpool) Annual Meeting
Invited Session
Acquisition and sharing of data in Alzheimer’s Disease Research
Marcus Jepson
2017 (Liverpool) Annual Meeting
Contributed Session
Adapting the QuinteT Recruitment Intervention (QRI) to optimise recruitment in an ongoing randomised controlled trial
Rachel Blundred
2017 (Liverpool) Annual Meeting
Contributed Session
Adapting trial design for challenging populations: How the Rational MCC trial was designed to account for a rare, aggressive cancer in an elderly and diverse population
Christopher Jennison
2017 (Liverpool) Annual Meeting
Educational Session
Adaptive Designs Showcase and Panel Discussion
Christopher Jennison
2017 (Liverpool) Annual Meeting
Invited Session
Adaptive Designs Showcase and Panel Discussion
Deepak Parashar
2017 (Liverpool) Annual Meeting
Contributed Session
Adaptive enrichment design for randomised clinical trials with predictive biomarkers
Ben Saville, Ph.D.
2017 (Liverpool) Annual Meeting
Educational Session
Adaptive Multi-arm Platform Trials
Brett Hanscom
2017 (Liverpool) Annual Meeting
Contributed Session
Adaptive Non-Inferiority Margins under Obervable Non-Constancy
Yu Lan
2017 (Liverpool) Annual Meeting
Contributed Session
Adaptive Prediction of Event Times in Clinical Trials
Laura Flight
2017 (Liverpool) Annual Meeting
Invited Session
Adaptive Study Designs and Health Economic Evaluations
Tom Morris
2017 (Liverpool) Annual Meeting
Contributed Session
Adjusting trial analyses for continuous stratification variables
Kirsty Rhodes
2017 (Liverpool) Annual Meeting
Contributed Session
Adjusting trial results for biases in meta-analysis: combining generic evidence on bias with detailed trial assessment
Rebecca Mercieca-Bebber
2017 (Liverpool) Annual Meeting
Contributed Session
Administering patient-reported outcome questionnaires in Australian cancer trials: the roles, experiences, training received and needs of site coordinators
Adwoa Hughes-Morley
2017 (Liverpool) Annual Meeting
Educational Session
Advancing trial efficiency through embedded recruitment and retention trials
Vichithranie MADURASINGHE
2017 (Liverpool) Annual Meeting
Contributed Session
Adverse outcomes in non-drug intervention trials: what and how these are recorded
Heather Bagley
2017 (Liverpool) Annual Meeting
Contributed Session
Agreeing outcomes that matter to patients – what are the challenges?
Cody Chiuzan
2017 (Liverpool) Annual Meeting
Invited Session
Alternative Endpoints and Dose Selection Methods in Early-Phase Cancer Trials
James Dignam
2017 (Liverpool) Annual Meeting
Invited Session
Alternative metrics and inference tools in clinical trials with time-to-event data: Beyond the hazard ratio and log-rank test.
Vicky Tsipouri
2017 (Liverpool) Annual Meeting
Contributed Session
Ambulatory oxygen in fibrotic lung disease (AmbOx): study protocol for a randomised controlled trial.
Maria Altzerinakou
2017 (Liverpool) Annual Meeting
Contributed Session
An adaptive design for the identification of the optimal dose using joint modelling of efficacy and toxicity in phase I/II clinical trials of molecularly targeted agents
Melina Dritsaki
2017 (Liverpool) Annual Meeting
Contributed Session
An annotated guideline to the use of a Health Economics Analysis Plan (HEAP) alongside randomised controlled trials.
Bethan Copsey
2017 (Liverpool) Annual Meeting
Contributed Session
An assessment of the design and dissemination of Phase I clinical trials: where can we improve?
Austin Horn
2017 (Liverpool) Annual Meeting
Contributed Session
An ethical analysis of the FIRST Trial: Addressing ethical challenges in pragmatic cluster randomized trials of policy interventions targeting healthcare providers
Fan Li
2017 (Liverpool) Annual Meeting
Contributed Session
An evaluation of constrained randomization for the design and analysis of group-randomized trials with binary outcomes
Emma Clark
2017 (Liverpool) Annual Meeting
Contributed Session
An evaluation of statistical methods for predicting timelines for reaching target number of events in clinical trials with time-to-event endpoints
Nicola Mills
2017 (Liverpool) Annual Meeting
Contributed Session
An evaluation of the impact of QuinteT RCT recruitment training on the self-confidence and self-assessed recruitment practice of recruiters to surgical trials
Joseph Rausch
2017 (Liverpool) Annual Meeting
Contributed Session
An Evaluation of Treatment Effect Estimators When Primary Outcome Data are Missing in Longitudinal Randomized Clinical Trials
Leila Rooshenas
2017 (Liverpool) Annual Meeting
Contributed Session
An intervention to optimise recruitment in challenging RCTs: implementation of the 'Quintet Recruitment Intervention' across eight pilot/feasibility RCTs
Rebecca Simpson
2017 (Liverpool) Annual Meeting
Contributed Session
AN INVESTIGATION OF THE FACTORS WHICH INFLUENCE CHILDREN WITH ASTHMA HAVING UNSCHEDULED MEDICAL CONTACTS AROUND THE START OF THE NEW SCHOOL YEAR IN ENGLAND AND WALES – A MIXED METHODS STUDY
ENASS DURO
2017 (Liverpool) Annual Meeting
Contributed Session
An investigation of the methods used to design, analysis and quantify non-inferiority margins in four medical journals in a 12 month time period
Andrew Brand
2017 (Liverpool) Annual Meeting
Contributed Session
An Online Tool for Exploring Recruitment Achievability for a Feasibility and Pilot Studies in the UK.
Sara Khalid
2017 (Liverpool) Annual Meeting
Contributed Session
An Oxford Knee Score cut-off point to identify patients with chronic pain after knee replacement for a complex intervention trial
Rebecca Evans
2017 (Liverpool) Annual Meeting
Contributed Session
Analysis challenges in Blood Stream Infection: Focus on outcomes study
Ross Peterson
2017 (Liverpool) Annual Meeting
Contributed Session
Analysis of an ordinal endpoint for use in evaluating treatments for severe influenza requiring hospitalization
Laurent Billot
2017 (Liverpool) Annual Meeting
Contributed Session
Analysis of the Head Position in Stroke Trial (HeadPoST): an international cluster randomised cross-over trial
Athanasia Gravani
2017 (Liverpool) Annual Meeting
Contributed Session
ANALYSIS OF TRIAL-SPECIFIC TRAINING DURING THE SITE INITIATION PHASE: THE ATLAS STUDY
Rebecca Playle
2017 (Liverpool) Annual Meeting
Contributed Session
Analysis strategies for two-level clustering in one arm of a randomised group therapy trial set in Cardiff Prison
Susanna Dodd
2017 (Liverpool) Annual Meeting
Invited Session
Application of causal analysis in clinical trials
Mark Van Natta
2017 (Liverpool) Annual Meeting
Contributed Session
Application of Recent NEJM Recommendations for Supplementary Analyses of Positive or Failed Randomized Clinical Trials
Wenle Zhao
2017 (Liverpool) Annual Meeting
Contributed Session
Architecture design of an automated study drug distribution coordination module integrated in a web-based clinical trial management system
Yuan Huang
2017 (Liverpool) Annual Meeting
Contributed Session
ASCERTAINING STUDY PARTICIPANT SAFETY USING CENTRALIZED ELECTRONIC MEDICAL RECORDS IN A CLINICAL TRIAL SETTING --- LESSONS LEARNED FROM THE VETERANS AFFAIRS NEPHRON-D TRIAL
Charlotte Murkin
2017 (Liverpool) Annual Meeting
Contributed Session
Assessing clinically relevant endpoints in a pragmatic trial: Development of a measure to identify relevant clinical symptoms.
Elaine Toomey
2017 (Liverpool) Annual Meeting
Contributed Session
Assessing implementation fidelity in clinical trials of behaviour change interventions
Karen Barnes
2017 (Liverpool) Annual Meeting
Contributed Session
Assessing the impact of a funder’s recommendation on consideration and uptake of core outcome sets in funding applications
Peter Godolphin
2017 (Liverpool) Annual Meeting
Contributed Session
Assessing the impact of independent adjudication of serious adverse events on the safety results of the Efficacy of Nitric Oxide in Stroke (ENOS) Trial
Sabine Landau
2017 (Liverpool) Annual Meeting
Contributed Session
Assessing treatment effect moderation in trials of psychological interventions: A case for individual participant data meta-analysis of pooled trials
Nada Alsowaida
2017 (Liverpool) Annual Meeting
Contributed Session
Assessment of the reporting quality of RCTs conducted in Saudi Arabia: A systematic review
Chris Rogers
2017 (Liverpool) Annual Meeting
Contributed Session
Audio-recording recruitment consultations – an exploratory study in two RCTs to investigate the impact on randomisation rates
Elizabeth Hill
2017 (Liverpool) Annual Meeting
Contributed Session
Automated solution for importing lab test results from a laboratory information management system into an electronic data capture system
Elizabeth Hill
2017 (Liverpool) Annual Meeting
Contributed Session
Automated solution for tracking electronic case report form completion
Ting Wang
2017 (Liverpool) Annual Meeting
Contributed Session
Auxiliary-variable-enriched Biomarker Stratified Design
Matthew Sydes, MRC CTU at UCL, London, UK
2017 (Liverpool) Annual Meeting
Invited Session
Balancing on-site and central monitoring: where does new evidence leads us?
Marina Zaki
2017 (Liverpool) Annual Meeting
Contributed Session
Barriers and Facilitators to Statistical Rigour in Clinical Trials - Emerging Themes from the Literature
Adedayo Oke
2017 (Liverpool) Annual Meeting
Contributed Session
Barriers to recruitment from primary care into a trial in secondary care settings: experience from the feasibility study of IBIS-3 trial
Shalini Santhakumaran
2017 (Liverpool) Annual Meeting
Contributed Session
Bayesian methods for informative missingness in longitudinal intensive care data
Chris Newby
2017 (Liverpool) Annual Meeting
Contributed Session
Bayesian prediction of the Intra-cluster correlation for sample size calculation of cluster randomised trials
Xinxue Liu
2017 (Liverpool) Annual Meeting
Contributed Session
Bayesian predictive probability design in single-arm cancer phase II trials: is it superior to Frequentist design?
Sonia Davis
2017 (Liverpool) Annual Meeting
Contributed Session
Best Practices for Reporting Safety Data to Data Monitoring Committees
Dikla Blumberg
2017 (Liverpool) Annual Meeting
Contributed Session
Best practices for study drug management and accountability throughout the study lifecycle in multi-site randomized controlled trials
Natalie Blencowe
2017 (Liverpool) Annual Meeting
Contributed Session
Beyond blinding: a systematic review to explore performance bias in surgical RCTs
Gita Thanarajasingam
2017 (Liverpool) Annual Meeting
Contributed Session
Beyond Maximum Grade: A Novel Longitudinal Toxicity over Time (ToxT) Adverse Event Analysis for Targeted Therapy Trials in Lymphoma
Allan Wilson
2017 (Liverpool) Annual Meeting
Contributed Session
Big Data Analytics and the Elephant in the Room
Sarah Kernaghan
2017 (Liverpool) Annual Meeting
Contributed Session
Biological sample collection: considerations and lessons learnt at ICR-CTSU
David Raunig
2017 (Liverpool) Annual Meeting
Contributed Session
Biomarker Validation as a Clinical Trial Endpoint: What works and what doesn’t
Miranta Antoniou
2017 (Liverpool) Annual Meeting
Contributed Session
Biomarker-guided clinical trial designs: Sample size calculations with survival endpoints
Ella Zadorozny
2017 (Liverpool) Annual Meeting
Contributed Session
Biospecimen Management System that Streamlines Processes and Reduces Inherent Challenges
Michael Grayling
2017 (Liverpool) Annual Meeting
Contributed Session
Blinded and unblinded sample size re-estimation procedures for stepped wedge cluster randomised trials
Pascal Probst
2017 (Liverpool) Annual Meeting
Contributed Session
Blinding in randomized controlled trials in general and abdominal surgery: a systematic review and empirical study
Paul McGarry
2017 (Liverpool) Annual Meeting
Contributed Session
Breaking up is hard to do: Letting go of paper case report forms (CRFs) and the challenges of adapting data management processes to remote data entry (RDE)
Julia Wade
2017 (Liverpool) Annual Meeting
Contributed Session
Bridging the gap between knowledge and practice: methods developed within the ProtecT trial to optimise implementation of findings in clinical policy and practice.
Katie Flaherty
2017 (Liverpool) Annual Meeting
Contributed Session
Brief consent forms enable rapid enrolment in acute clinical trials: Data from the on-going Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2) study.
Robbie Wilson
2017 (Liverpool) Annual Meeting
Contributed Session
Building a generic Drug Supply Management system for eCRF systems – challenges and experience gained
Jonathan Gibb
2017 (Liverpool) Annual Meeting
Contributed Session
Building a new EDC in 2016
Cushla Cooper
2017 (Liverpool) Annual Meeting
Contributed Session
Building a relationship with industry – an academic’s experience working with Zimmer Biomet.
Ileana Baldi
2017 (Liverpool) Annual Meeting
Contributed Session
Building comprehensive searches through a Machine Learning approach for systematic reviews
The RELEASE Collaboration
2017 (Liverpool) Annual Meeting
Contributed Session
Building on the past: systematic identification, data extraction and synthesis of pre-existing individual stroke patient datasets to inform the development and design of future clinical trials.
Nils Ternès
2017 (Liverpool) Annual Meeting
Contributed Session
Calculating expected survival from high-dimensional Cox models with treatment-by-biomarker interactions in randomized clinical trials
Jessica Kendall
2017 (Liverpool) Annual Meeting
Contributed Session
Calibrated Phase II Oncology Design in a Bayesian Setting
Kirsteen Goodman
2017 (Liverpool) Annual Meeting
Contributed Session
Can behaviour change theory increase questionnaire response rates within trials?
Ranjit Lall
2017 (Liverpool) Annual Meeting
Contributed Session
Can Complex Intervention clinical trials capture treatment effects using a single primary outcome?
Peter McCulloch, Chair, IDEAL Collaboration
2017 (Liverpool) Annual Meeting
Invited Session
CAN PROSPECTIVE COLLABORATIVE COHORT STUDIES EASE THE WAY TO RCTS OF COMPLEX INTERVENTIONS?
Diane Whitham
2017 (Liverpool) Annual Meeting
Contributed Session
Can site recruitment be predicted? Results of a retrospective, blinded evaluation of a site selection questionnaire in five multicentre trials
Seonaidh Cotton
2017 (Liverpool) Annual Meeting
Contributed Session
Can trial managers predict whether sites will recruit to target or not? Results from the Estimating Site Performance (ESP) study
Carlo Lancia
2017 (Liverpool) Annual Meeting
Contributed Session
Causal inference with randomised clinical trials of chemotherapy: the importance of well-documented treatment side-effects
Trisha Boekhoudt
2017 (Liverpool) Annual Meeting
Contributed Session
CENTRAL CHART REVIEW OF COMPLEX OUTCOMES
Caitlyn Ellerbe
2017 (Liverpool) Annual Meeting
Invited Session
Challenges and Potential Solutions to Translating a Research Idea into a Clinical Trial - Case Studies from the StrokeNet Disease Network
Julie Croft
2017 (Liverpool) Annual Meeting
Contributed Session
Challenges faced during implementation of a surgical clinical trial
Megan Wirth
2017 (Liverpool) Annual Meeting
Contributed Session
Challenges in Implementing and Managing Clinical Trials in Developing Countries: Lessons Learned by The National Cancer Institute’s (NCI) AIDS Malignancy Consortium (AMC)
Laura Cavaliere
2017 (Liverpool) Annual Meeting
Contributed Session
Challenges in teaching clinical trials: the experience of teaching biostatistics in online post-graduate academic courses, target to industrial biometrician
Helena Smartt
2017 (Liverpool) Annual Meeting
Contributed Session
Challenges in the analysis of a randomised controlled trial with retrospective consenting: the RAPIDO study
Dominic Hague
2017 (Liverpool) Annual Meeting
Contributed Session
Changing platforms without stopping the train : A Data Management Perspective on the operational aspects of adaptive platform trials
Anne Daykin
2017 (Liverpool) Annual Meeting
Contributed Session
Changing roles and relationships within trial oversight: An ethnographic study of eight clinical trials facing challenges
Era Prakash
2017 (Liverpool) Annual Meeting
Invited Session
Changing the Way We Recruit Patients for Clinical Trials
Louise Roper
2017 (Liverpool) Annual Meeting
Contributed Session
CHILDREN AND YOUNG PEOPLE’S VIEWS ON RESEARCH WITHOUT PRIOR CONSENT IN LIFE THREATENING SITUATIONS: A QUALITATIVE STUDY
Kim Harman
2017 (Liverpool) Annual Meeting
Contributed Session
Chinese Herbal Medicine (CHM) for Recurrent UTIs in Women, a feasibility trial.
Tim Morris
2017 (Liverpool) Annual Meeting
Contributed Session
Choosing between cross-over and re-randomisation designs for conditions with multiple treatment episodes
Barbara Hawkins
2017 (Liverpool) Annual Meeting
Contributed Session
Citation of Articles Published in Clinical Trials: Design Articles vs. Others
Rhiannon Macefield
2017 (Liverpool) Annual Meeting
Contributed Session
Clinical and psychometric validation of a new outcome measure: methods to assess measurement properties in the absence of a 'gold' standard
Ionut Bebu
2017 (Liverpool) Annual Meeting
Invited Session
Clinical Studies with Long-term Follow-up: Experiences and Lessons Learned
Claire Snowdon
2017 (Liverpool) Annual Meeting
Contributed Session
Clinical Trial Data and Tissue – Considerations for Responsible Sharing
Gabriele Dreier
2017 (Liverpool) Annual Meeting
Contributed Session
Clinical Trial Units of Medical Scientific Societies to close Evidence Gaps
Abhik Das
2017 (Liverpool) Annual Meeting
Contributed Session
Clinical trials in neonatology: Design and analyses issues
Laura Pankhurst
2017 (Liverpool) Annual Meeting
Contributed Session
Clinical trials in organ donation and transplantation in the UK - benefits and challenges
Joerg Hasford
2017 (Liverpool) Annual Meeting
Contributed Session
Clinical Trials: increasing value, reducing waste - the potential role of Ethics Committees
Elizabeth Wright
2017 (Liverpool) Annual Meeting
Contributed Session
Cluster Randomized Clinical Trials: Can they be found in PubMed and clinical trial registries and do they adhere to CONSORT guidelines?
Lucy Brading
2017 (Liverpool) Annual Meeting
Contributed Session
Collating the evidence base to facilitate patient and public involvement in core outcome set development – a qualitative meta-synthesis
Lucy Culliford
2017 (Liverpool) Annual Meeting
Contributed Session
Collecting trial quality data about complications routinely: a study within a study to maximize efficiency
Matthew Sydes, (1) MRC CTU at UCL, London, UK; (2) MRC London Hub for Trials Methodology Research, London, UK
2017 (Liverpool) Annual Meeting
Invited Session
Communicating trial results to participants
Lei Clifton
2017 (Liverpool) Annual Meeting
Contributed Session
Comparing different ways of calculating sample size for a randomised controlled trial using baseline and post-intervention measurements
Caroline Rick
2017 (Liverpool) Annual Meeting
Contributed Session
Comparing the challenges of the management of trials of medical tests versus randomised controlled trials of health care interventions.
James Griffin
2017 (Liverpool) Annual Meeting
Contributed Session
Comparison and impact of prospective and retrospective falls data completion methods in the PreFIT trial: Results of a randomised methodology study within a trial (SWAT)
Lisa Woodhouse
2017 (Liverpool) Annual Meeting
Contributed Session
Comparison of global statistical analyses in patients with hyper-acute stroke: assessment of randomised trials of transdermal glyceryl trinitrate, a nitric oxide donor
Giovanna Culeddu
2017 (Liverpool) Annual Meeting
Contributed Session
Comparison of regression methods for the cost effectiveness analysis of clinical trials with a small population size: the SYCAMORE and FolATED trials.
Julia Edwards
2017 (Liverpool) Annual Meeting
Contributed Session
Concealing the randomised allocation in trials: experience from the Thermic trials
Stanley Musgrave
2017 (Liverpool) Annual Meeting
Contributed Session
Concepts important to the design of an innovative risk register in general practice databases – developing methodology from ARRISA-UK
Shah-Jalal Sarker
2017 (Liverpool) Annual Meeting
Contributed Session
Concurrent versus sequential addition of diethylstilbestrol with dexamethasone in the treatment of castration-resistant prostate cancer: An exploratory analysis
David Robertson
2017 (Liverpool) Annual Meeting
Contributed Session
Conditionally unbiased estimation in two-stage adaptive trials with unknown variances
Katie Griffin
2017 (Liverpool) Annual Meeting
Contributed Session
Conduct of a Precision Medicine Trial: Screening, Tissue Adequacy, Study Registration, and Reasons For Not Participating on Lung-MAP (Lung Cancer Master Protocol)
Professor Amanda Farrin
2017 (Liverpool) Annual Meeting
Invited Session
Conducting trials in adult populations with diminished capacity
Peter Mulhall
2017 (Liverpool) Annual Meeting
Contributed Session
Conducting Trials with hard to recruit disabled populations: A systematic review of the methodological challenges reported in the literature.
Julia Sanders
2017 (Liverpool) Annual Meeting
Contributed Session
Consent pathway options in trials of emergency interventions
Lawrence Mbuagbaw
2017 (Liverpool) Annual Meeting
Contributed Session
Considerations in designing equity-relevant clinical trials
Eve Jelstrom
2017 (Liverpool) Annual Meeting
Contributed Session
Considering Sex as a Biological Variable in Research Design, Data Analyses and Reporting
Rebecca Mister
2017 (Liverpool) Annual Meeting
Contributed Session
Consolidated trial management: An example of a purpose built Clinical Trial Management System for an Academic Research Organisation
Nicholas Magill
2017 (Liverpool) Annual Meeting
Contributed Session
Contamination in trials of complex interventions: measuring and accounting for it in the analysis of a trial
Lisa Woodhouse
2017 (Liverpool) Annual Meeting
Contributed Session
Continue or Stop: the rationale for early closedown of a clinical trial as a result of stopping rules within the data monitoring committee charter
Masha Kocherginsky
2017 (Liverpool) Annual Meeting
Contributed Session
Continuous Safety Monitoring in Large Phase I Cancer Clinical Trials with Multiple Expansion Cohorts
Haolun Shi
2017 (Liverpool) Annual Meeting
Contributed Session
Control of type I error rates in Bayesian group sequential designs
Joanna Thorn
2017 (Liverpool) Annual Meeting
Contributed Session
Core items for a standardised resource-use measure (ISRUM): expert Delphi consensus survey
Amarnath Vijayarangan
2017 (Liverpool) Annual Meeting
Contributed Session
Cost Effective Interactive Live Clinical Data Monitoring Dashboards with Drill-Down
Baptiste Leurent
2017 (Liverpool) Annual Meeting
Contributed Session
Cost-effectiveness analysis of clinical trials with missing data: using multiple imputation to address data missing not at random
Ram Bajpai
2017 (Liverpool) Annual Meeting
Contributed Session
Could adaptive research designs be useful in designing an effective eHealth intervention? A methodological analysis
Robin Bechhofer
2017 (Liverpool) Annual Meeting
Educational Session
Creating Effective Reports for Data Monitoring Committees (DMCs)
Kent Koprowicz
2017 (Liverpool) Annual Meeting
Contributed Session
Current Trends in Data Monitoring Committees
Shaun Treweek
2017 (Liverpool) Annual Meeting
Invited Session
Data and Biospecimen Sharing: Enhancing Collaborative Science Globally
Michelle Steven
2017 (Liverpool) Annual Meeting
Contributed Session
Data Management Lifecycle Evaluation
Virginia Chiocchia
2017 (Liverpool) Annual Meeting
Contributed Session
Data Monitoring Committee overseeing multiple international randomised controlled trials
Lynn A. Sleeper
2017 (Liverpool) Annual Meeting
Educational Session
Data Monitoring Committees (DMCs): Member Responsibilities and Interpretation of DMC Reports for Effective Decision-Making
Rebecca DerSimonian
2017 (Liverpool) Annual Meeting
Invited Session
Data Monitoring Committees: Current Issues and Challenges
Raymond Bain, Ph.D.
2017 (Liverpool) Annual Meeting
Educational Session
Data Monitoring Committees: Multi-stakeholder Recommendations and Hands-on Experience from CTTI and the MRCT Center
Katie Flaherty
2017 (Liverpool) Annual Meeting
Contributed Session
Data validation traffic light system: data from the Tranexamic acid for IntraCerebral Haemorrhage (TICH-2) trial.
Chris Harbron
2017 (Liverpool) Annual Meeting
Contributed Session
Decision Making in the Face of Biomarker Uncertainty
Sharon Kean
2017 (Liverpool) Annual Meeting
Contributed Session
Decisions, decisions: bespoke EDC?
Peter Kaufmann
2017 (Liverpool) Annual Meeting
Contributed Session
Decomposing the effects of the study population on null results: the Look AHEAD trial.
Andrew Forbes
2017 (Liverpool) Annual Meeting
Contributed Session
Decomposition of the treatment effect estimator in stepped wedge trials: Understanding the horizontal and vertical contributions
Babak Choodari-Oskooei
2017 (Liverpool) Annual Meeting
Contributed Session
DEFINING THE FAMILY OF PAIRWISE COMPARISONS IN MULTI-ARM MULTI-STAGE (MAMS) PLATFORM TRIALS
Sarah Gaussoin
2017 (Liverpool) Annual Meeting
Contributed Session
Dementia Outcomes After Addition of Proxy-based Assessments for Deceased or Proxy-dependent Participants
Yuanyuan Kong
2017 (Liverpool) Annual Meeting
Contributed Session
Demographic and Baseline Characteristics of Patients in China Registry of Hepatitis B (CR-HepB)
Jenny Donovan
2017 (Liverpool) Annual Meeting
Contributed Session
Demonstrating the external validity of a randomised controlled trial: the design and generalizability of the ProtecT prostate cancer trial
Ian White
2017 (Liverpool) Annual Meeting
Educational Session
Demystifying causal inference: Assessing efficacy when patients depart from randomised treatments
Miss Conroy
2017 (Liverpool) Annual Meeting
Contributed Session
Design and analysis of the learning curve and clustering effects in randomised surgical trials – a review of current practice
Rema Raman, PhD
2017 (Liverpool) Annual Meeting
Invited Session
Design and Biostatistical Considerations in Alzheimer’s Disease clinical trials
Rick Chappell
2017 (Liverpool) Annual Meeting
Invited Session
Design and conduct of Oncology Clinical Trials: A Session in Memory of Daniel J. Sargent (1970-2016)
Richard Holubkov
2017 (Liverpool) Annual Meeting
Contributed Session
DESIGN AND COORDINATION OF THE DECAAF II RANDOMIZED INTERNATIONAL TRIAL
Wenle Zhao
2017 (Liverpool) Annual Meeting
Educational Session
Design and implementation of better and simple randomization algorithms with low allocation predictability, accurate allocation targeting, and strong baseline covariate balancing
Lehana Thabane
2017 (Liverpool) Annual Meeting
Invited Session
Design and Methodological Issues in Registry-based Randomized Controlled Trials
Isoken Odia
2017 (Liverpool) Annual Meeting
Contributed Session
DESIGN ISSUES OF A NON-INFERIORITY TRIAL: Prompt Panretinal Photocoagulation Versus Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy (A tale of Two Diseases)
Kristian Brock
2017 (Liverpool) Annual Meeting
Contributed Session
Design of a practice-changing trial in the ultra-rare condition of Wolfram Syndrome
Mary Redman
2017 (Liverpool) Annual Meeting
Contributed Session
Design, conduct, and analysis of a master protocol within an evolving landscape of standard of care: The Lung-MAP Trial
Mark Espeland
2017 (Liverpool) Annual Meeting
Contributed Session
Designing Clinical Trials with Age-Related Multiple Morbidity Outcomes
Eftychia Psarelli
2017 (Liverpool) Annual Meeting
Contributed Session
Designing trial outcomes for rare diseases
Sujata Patil
2017 (Liverpool) Annual Meeting
Contributed Session
Designing trials that aim to evaluate therapies that target brain metastases in cancer patients: challenges and recommendations
Deborah Donnell
2017 (Liverpool) Annual Meeting
Contributed Session
Detection of incomplete data in surveillance and impact of missing data in assessment of effectiveness of financial incentives of viral load suppression in HPTN 065
Alexina Mason
2017 (Liverpool) Annual Meeting
Contributed Session
Developing a Bayesian adaptive design for a Phase I clinical trial: a case study for a novel HIV treatment
Megan Wirth
2017 (Liverpool) Annual Meeting
Contributed Session
Developing a Comprehensive Site Selection Process for a Cancer Network in a Resource-Limited Settings in Sub-Saharan Africa
Lydia Emerson
2017 (Liverpool) Annual Meeting
Contributed Session
Developing a framework to aid purposive sampling in process evaluation of a critical care trial
Kayla Daniels
2017 (Liverpool) Annual Meeting
Contributed Session
Developing a Web-Based Central Laboratory Shipment Scheduler and Information System
Martin Landray
2017 (Liverpool) Annual Meeting
Contributed Session
DEVELOPING NOVEL ENDPOINTS, GENERATED USING MOBILE TECHNOLOGY, FOR USE IN CLINICAL TRIALS: A CLINICAL TRIALS TRANSFORMATION INITIATIVE (CTTI) PROJECT
Martin Landray
2017 (Liverpool) Annual Meeting
Invited Session
Developing Novel Endpoints, Generated using Mobile Technology, for use in Clinical Trials: A Clinical Trials Transformation Initiative (CTTI) Project
Jonathan Gibb
2017 (Liverpool) Annual Meeting
Contributed Session
Developing Tablet Based EDC Apps
Athanasia Gravani
2017 (Liverpool) Annual Meeting
Contributed Session
DEVELOPMENT AND FIRST EVALUATION OF THE ATLAS TRAINING TOOLKIT FOR CLINICAL TRIALS
Helen Richmond
2017 (Liverpool) Annual Meeting
Contributed Session
Development of a complex exercise intervention for prevention of shoulder dysfunction in high-risk women following treatment for breast cancer: PReventionOf Shoulder ProblEms tRial (PROSPER)
Vikki Wylde
2017 (Liverpool) Annual Meeting
Contributed Session
Development of a complex intervention for patients with chronic pain after knee replacement
Sarah Lawton
2017 (Liverpool) Annual Meeting
Contributed Session
Development of a Health Informatics Working Group to enhance the conduct of Clinical Trials in Primary Care
Sharon Kean
2017 (Liverpool) Annual Meeting
Contributed Session
Development of a safe haven analytical platform
Susanne Finnegan
2017 (Liverpool) Annual Meeting
Contributed Session
Development of complex interventions to prevent falls and fractures in older people living in the community: The Prevention of Fall Injury Trial (PreFIT)
Michael Schlussel
2017 (Liverpool) Annual Meeting
Contributed Session
DEVELOPMENT OF THE CORKA TRIAL SCREENING TOOL FOR IDENTIFYING PATIENTS AT INCREASED RISK OF POOR OUTCOME FOLLOWING KNEE REPLACEMENT
Julie Duncan Millar
2017 (Liverpool) Annual Meeting
Contributed Session
Development of the Standardising Measures in Arm Rehabilitation Trials for stroke (SMART) Toolbox (Work in progress)
Amber Randall
2017 (Liverpool) Annual Meeting
Contributed Session
DMC Report Production: Considering a Risk-Based Approach to Quality Control
Jessica Wood
2017 (Liverpool) Annual Meeting
Contributed Session
Do higher monetary incentives improve response rates part-way through a randomised control trial?
Jackie Martin-Kerry
2017 (Liverpool) Annual Meeting
Contributed Session
Do multimedia resources increase the quality of information provision and rate of recruitment in trials involving children and adolescents?: Protocol for the TRECA study
Lauren Greenberg
2017 (Liverpool) Annual Meeting
Contributed Session
Do trialists adequately pre-specify their statistical analysis approach? A review and re-analysis
Adwoa Hughes-Morley
2017 (Liverpool) Annual Meeting
Contributed Session
Does advertising patient and public involvement in a trial to potential participants improve recruitment and response rates? An embedded cluster randomised trial
Lucy Culliford
2017 (Liverpool) Annual Meeting
Contributed Session
Does appearance matter? A study within a study
Richard Holubkov
2017 (Liverpool) Annual Meeting
Contributed Session
DSMB Monitoring of the Therapeutic Hypothermia After Pediatric Cardiac Arrest (THAPCA) Trials
Ashley Hogan
2017 (Liverpool) Annual Meeting
Contributed Session
Dynamic Manuscript Development and Tracking for Clinical Trial Publications
Gian Luca Di Tanna
2017 (Liverpool) Annual Meeting
Contributed Session
Economic evaluation alongside Stepped Wedge Trials: a systematic review and a proposal of analysis
Allison Furey
2017 (Liverpool) Annual Meeting
Contributed Session
Effective Graphical Analyses of Adverse Events in DMC Reports
Sean Strong
2017 (Liverpool) Annual Meeting
Contributed Session
Effective teamwork is crucial to maximising recruitment to randomised controlled trials in surgical oncology
Seonaidh Cotton
2017 (Liverpool) Annual Meeting
Contributed Session
Efficiencies in multi-centre RCTs – what lessons can be learned from a trial with more than 100 recruitment sites?
Kris McGill
2017 (Liverpool) Annual Meeting
Contributed Session
Efficiency of Recruitment to Stroke Rehabilitation Randomised Controlled Trials: Secondary Analysis of Recruitment Data
Toshimitsu Hamasaki
2017 (Liverpool) Annual Meeting
Contributed Session
Efficient group-sequential designs for monitoring two time-to-event outcomes in clinical trials
Charlotte Friend
2017 (Liverpool) Annual Meeting
Contributed Session
Electronic data capture; changing data management at ICR-CTSU
Debra Housel
2017 (Liverpool) Annual Meeting
Invited Session
Electronic Medical Record (EMR) Use in Clinical Research Monitoring: Challenges and Solutions
Pamela Tenaerts
2017 (Liverpool) Annual Meeting
Contributed Session
Embedding Randomized Clinical Trials within Registries: How Feasible?
Suzanne Hartley
2017 (Liverpool) Annual Meeting
Contributed Session
Embedding trials into established service improvement initiatives: challenges and lessons from an implementation laboratory.
Yuanyuan Liang
2017 (Liverpool) Annual Meeting
Contributed Session
Engaging hard-to-reach communities for community-partnered research: A comparison of two non-probability sampling methods
Jonathan Gibb
2017 (Liverpool) Annual Meeting
Contributed Session
Ensuring a GCP compliant audit trail for EDC/EPROM
Amanda Lilley-Kelly
2017 (Liverpool) Annual Meeting
Contributed Session
ENSURING RESEARCH QUALITY IN CARE HOME TRIALS: LEARNING FROM NHS GOVERNANCE PROCEDURES
Amanda Lilley-Kelly
2017 (Liverpool) Annual Meeting
Invited Session
Ensuring Research quality in Care Home trials: Learning from NHS governance procedures
Laura Lovato
2017 (Liverpool) Annual Meeting
Educational Session
Essentials of Randomized Clinical Trials
Charles Opondo
2017 (Liverpool) Annual Meeting
Contributed Session
Estimating intervention effect in cluster randomised controlled trials with non-compliance
Kirsty Garfield
2017 (Liverpool) Annual Meeting
Contributed Session
Estimating the cost of prescribed medications in economic evaluation: does the current method reflect the true cost to the English NHS? Evidence from the COMET feasibility study.
Laura Mandefield
2017 (Liverpool) Annual Meeting
Contributed Session
Estimating the underlying overall and centre recruitment rates in external pilot trials- how many centre-months of recruitment data do we need? A case study of the BEADS pilot trial.
Cory Goldstein
2017 (Liverpool) Annual Meeting
Contributed Session
Ethical issues in individual-cluster trials: beyond the Ottawa Statement
Thomas Jaki
2017 (Liverpool) Annual Meeting
Invited Session
Evaluating medicines when recruitment is ethically and/or practically challenging
Matthias Pierce
2017 (Liverpool) Annual Meeting
Contributed Session
Evaluating personalised treatment recommendations using randomised controlled trials
Caroline Fairhurst
2017 (Liverpool) Annual Meeting
Contributed Session
Evaluating the effectiveness of remote versus on-site initiation visits: an embedded randomised controlled feasibility cluster trial within the SWIFFT trial
Antonia Marsden
2017 (Liverpool) Annual Meeting
Contributed Session
Evaluating treatment effect modification on the additive scale for the evaluation of predictive markers
Laurent Billot
2017 (Liverpool) Annual Meeting
Contributed Session
Evaluation of a state-wide chronic disease management program on health service utilisation using a propensity-matched control group
Federico Rotolo
2017 (Liverpool) Annual Meeting
Contributed Session
Evaluation of Failure Time Surrogate Endpoints in Individual Patient Data Meta-Analyses of randomized clinical trials. A Poisson Approach
Katie Gillies
2017 (Liverpool) Annual Meeting
Contributed Session
EvaLuation of Interventions for informed Consent for randomIsed controlled Trials (ELICIT): results from a systematic review and interviews towards developing a core outcome set.
Deirdre Hurley
2017 (Liverpool) Annual Meeting
Contributed Session
Evaluation of Recruitment Procedures to the Self-management of Osteoarthritis and Low back pain through Activity and Skills (SOLAS) cluster randomised controlled feasibility trial [ISRCTN 49875385]
David Beard
2017 (Liverpool) Annual Meeting
Contributed Session
Evidence based evaluation of practice using the IDEAL-Physio framework. A strategic method of evaluating innovation and current practice.
Rebecca Haydock
2017 (Liverpool) Annual Meeting
Contributed Session
Evolution of a recruitment strategy between secondary and primary care during the recruitment phase of the Fourfold Asthma (FAST) Trial
Sandra Galvin
2017 (Liverpool) Annual Meeting
Invited Session
Exemplars of the successful involvement of the public in randomised trial design.
Gillian Gyte
2017 (Liverpool) Annual Meeting
Contributed Session
Explaining randomisation to potential clinical trial participants
Neil Corrigan
2017 (Liverpool) Annual Meeting
Contributed Session
Exploring and adjusting for potential learning effects in ROLARR - a randomised controlled surgical trial
Amarnath Vijayarangan
2017 (Liverpool) Annual Meeting
Contributed Session
Exploring Automated Free SMS from Email in Clinical Trials
Jennifer Liddle
2017 (Liverpool) Annual Meeting
Contributed Session
Exploring discrepancies between long-term condition review consultation audio-recordings and computer template data (the ENHANCE pilot trial)
Paulina Szymczynska
2017 (Liverpool) Annual Meeting
Contributed Session
Exploring Retention Challenges and Strategies in Psychosis Trials: Patient and Trialist Perspectives
Joanne Chalmers
2017 (Liverpool) Annual Meeting
Contributed Session
Exploring the impact of priority setting partnerships in skin disease
Richard Hellyar
2017 (Liverpool) Annual Meeting
Contributed Session
Exploring understanding of Neural Stem Cell Transplantation (NSCT) as an intervention for Huntington’s disease (HD)
Denise Esserman
2017 (Liverpool) Annual Meeting
Contributed Session
Extending the Two-Stage Patient Preference Design for Binary Outcomes with Stratification
Iftekhar Khan
2017 (Liverpool) Annual Meeting
Contributed Session
Extrapolation of Utilities Between Disease Progression and Death in Cancer Trials for Economic Evaluation
Danielle Edwards
2017 (Liverpool) Annual Meeting
Contributed Session
Factors influencing recruitment in large randomised trials
Frances Sherratt
2017 (Liverpool) Annual Meeting
Contributed Session
Family perspectives on the feasibility of a corticosteroid induction regimen randomised controlled trial in juvenile idiopathic arthritis: Results of a qualitative study.
Rebecca Barnes
2017 (Liverpool) Annual Meeting
Contributed Session
Footprints in Primary Care: Using mixed methods to assess fidelity to a complex intervention for frequently attending patients
Amy Corneli
2017 (Liverpool) Annual Meeting
Contributed Session
Formative Research Findings on the Design of an Early Enrollment Clinical Trial on Hospital-Acquired Bacterial Pneumonia (HABP) and Ventilator-Associated Bacterial Pneumonia (VABP)
Paula Darby Lipman
2017 (Liverpool) Annual Meeting
Contributed Session
Framing the Conversation: Use of PRECIS-2 ratings to advance understanding of pragmatic trial design domains
Lucy Bradshaw
2017 (Liverpool) Annual Meeting
Contributed Session
Frequency of data collection in a randomised controlled trial for long term eczema management in children
Nelson Kinnersley
2017 (Liverpool) Annual Meeting
Contributed Session
From molecule to medicine: a case study in how a statistician can provide strategic input to drug development
Rick Grobbee
2017 (Liverpool) Annual Meeting
Invited Session
From the concept of pragmatic trials to a pragmatic and feasible study protocol
Lisa Douet
2017 (Liverpool) Annual Meeting
Contributed Session
Funding innovative study designs – The Efficacy and Mechanism Evaluation Programme
Claire Boyle
2017 (Liverpool) Annual Meeting
Contributed Session
FUNNEL PLOTS FOR STATISTICAL QUALITY CONTROL IN A LARGE, MULTI-SITE REGISTRY
Claire Diver
2017 (Liverpool) Annual Meeting
Contributed Session
Gatekeeping amongst allied health professionals: recruitment in stem cell trial of recovery enhancement-3 (STEMS-3) feasibility study
James Glasbey
2017 (Liverpool) Annual Meeting
Contributed Session
Generating student recruiters for randomised trials in surgery (GRANULE): A one-day course to empower a cohort of future surgical trialists
Tracey Davidson
2017 (Liverpool) Annual Meeting
Contributed Session
Going Green whilst maximising questionnaire response rates. Does size matter?
Sarah Lawton
2017 (Liverpool) Annual Meeting
Contributed Session
Good order is the foundation of all things: A strong project management structure underpins successful research at Keele CTU
Yi-Da Chiu
2017 (Liverpool) Annual Meeting
Contributed Session
Graphical display techniques for subgroup analysis
Colin Everett
2017 (Liverpool) Annual Meeting
Contributed Session
Graphical presentation of regression model diagnostics arising from using multiple imputation
Danni Liu
2017 (Liverpool) Annual Meeting
Contributed Session
Group Sequential Methods for Monitoring Multi-Arm Clinical Trials
Danila Azzolina
2017 (Liverpool) Annual Meeting
Contributed Session
HANDLING MISSING OR INCOMPLETE DATA IN A BAYESIAN NETWORK META-ANALYSIS FRAMEWORK
Danila Azzolina
2017 (Liverpool) Annual Meeting
Contributed Session
Handling poor accrual in adaptive trial setting: Bayesian Interim analysis of RESCUE Trial
Joanna Thorn
2017 (Liverpool) Annual Meeting
Contributed Session
Health economics analysis plans: the current state of play
Jonathan Deeks
2017 (Liverpool) Annual Meeting
Contributed Session
How accurately do trialists pre-specify sample sizes for test evaluation trials? The experience in NIHR funded trials in the HTA and EME programmes.
John Gregson
2017 (Liverpool) Annual Meeting
Contributed Session
How and when do competing risks influence results from clinical trials?
Melanie Bell
2017 (Liverpool) Annual Meeting
Contributed Session
How are researchers handling missing data in noninferiority trials? A systematic review
Rejina Verghis
2017 (Liverpool) Annual Meeting
Contributed Session
How are Surrogate Outcomes defined in Critical Care Trials? Preliminary results of a systematic review
Professor Paula Williamson
2017 (Liverpool) Annual Meeting
Invited Session
How can a trialist appraise and make use of core outcome sets and the COMET database?
Peter Bower
2017 (Liverpool) Annual Meeting
Contributed Session
How can incentives be designed and used to improve recruitment and retention in ways that are effective, efficient and ethical?
Carmel Conefrey
2017 (Liverpool) Annual Meeting
Contributed Session
How do recruiters present randomisation during trial recruitment? An evaluation of current practice
William Aitchison
2017 (Liverpool) Annual Meeting
Contributed Session
How do you detect and deal with compromised EDC accounts?
Siew Wan Hee
2017 (Liverpool) Annual Meeting
Contributed Session
How does prevalence affect the size of clinical trials for treatments of rare diseases?
Daisy Elliott
2017 (Liverpool) Annual Meeting
Contributed Session
How evidence is presented to potential participants in RCT recruitment consultations
Fang-Shu Ou
2017 (Liverpool) Annual Meeting
Contributed Session
How frequently should a disease be monitored? The interval length between observations in interval-censored data
Joanna Crocker
2017 (Liverpool) Annual Meeting
Contributed Session
How might patient and public involvement (PPI) improve recruitment and retention in surgical trials? A qualitative study exploring the views of trial staff and PPI contributors
Paul Wakim
2017 (Liverpool) Annual Meeting
Educational Session
How to avoid common errors related to design, statistical analysis and reporting of results of clinical trials
Professor Paul Brocklehurst
2017 (Liverpool) Annual Meeting
Invited Session
How to design implementation into your trial from the outset
Trish Groves
2017 (Liverpool) Annual Meeting
Educational Session
How to reduce research waste through publishing trials and protocols: an editor's guide
Joshua Feinberg
2017 (Liverpool) Annual Meeting
Contributed Session
IDEAL Framework and Recommendations: A literature review of its utilization by surgical innovators since 2009
Caroline Kristunas
2017 (Liverpool) Annual Meeting
Contributed Session
Identification of participants for a questionnaire and interview study investigating the feasibility issues encountered during stepped-wedge cluster randomised trials.
Anna Kearney
2017 (Liverpool) Annual Meeting
Contributed Session
Identifying effective retention strategies: A research agenda
Daniel Hill-McManus
2017 (Liverpool) Annual Meeting
Contributed Session
Identifying the optimal clinical pharmacological properties of potential future medicines using clinical trial simulation
Paul Thompson
2017 (Liverpool) Annual Meeting
Contributed Session
Image Modification Journaling for Reproducibility and Fraud Prevention
David Raunig
2017 (Liverpool) Annual Meeting
Contributed Session
Imaging endpoint eligibility in oncology trials: What works and what doesn’t
Kirsty Loudon
2017 (Liverpool) Annual Meeting
Contributed Session
Impact case study: Using PRECIS-2 to discuss the design of a pilot and feasibility study - Summary of Swallowing intervention Package (SiP)
Kevin Fain
2017 (Liverpool) Annual Meeting
Contributed Session
Impact of Results Reporting in ClinicalTrials.gov
Paul Brocklehurst
2017 (Liverpool) Annual Meeting
Contributed Session
Implementation in dental trials: an exploration of trial meta-processes
RANI JAYSWAL
2017 (Liverpool) Annual Meeting
Contributed Session
Implementation into Practice of Isotonic Regression for Simultaneous Assessment of Toxicity and Pharmacodynamic Endpoints in a Dose Escalation Trial
Helen Richmond
2017 (Liverpool) Annual Meeting
Contributed Session
Implementation into practice: the development, enhancement and delivery of an online training programme to support clinicians in the replication of the Back Skills Training (BeST) Programme in practice
Catherine Dillon
2017 (Liverpool) Annual Meeting
Contributed Session
Implementation of CTMS Functionality for Remote Monitoring of Informed Consents
Steven Weiner
2017 (Liverpool) Annual Meeting
Contributed Session
Implementation of Strategies to Improve Collection of a Challenging Laboratory Outcome in the Delivery Room
Lucy Bailey
2017 (Liverpool) Annual Meeting
Contributed Session
Implementing a Risk Based Monitoring Approach In The Early Phase Myeloma Portfolio at Leeds CTRU
Cody Chiuzan
2017 (Liverpool) Annual Meeting
Invited Session
Implementing adaptive designs: balancing the practical with the statistical
Duncan Appelbe
2017 (Liverpool) Annual Meeting
Contributed Session
Implementing and Running an online Trial – A case study using The REACT Trial
Ashley Hogan
2017 (Liverpool) Annual Meeting
Contributed Session
Implementing Mobile Electronic Patient Reported Outcomes (ePRO) in a Long-Term Trial with an Aging and Diverse Population
Alba Realpe
2017 (Liverpool) Annual Meeting
Contributed Session
Implementing training for recruiters based on a new simple six-step model to promote information sharing and recruitment to RCTs: Challenges and opportunities.
Rosie Harris
2017 (Liverpool) Annual Meeting
Contributed Session
Improving data quality though routine automated reporting using standard statistical software
Matthew Sydes
2017 (Liverpool) Annual Meeting
Contributed Session
IMPROVING KAPLAN–MEIER GRAPHS: BETTER PRESENTATION OF NUMBERS-AT-RISK, CUMULATIVE EVENTS AND MEASURES OF UNCERTAINTY
Jon Steingrimsson
2017 (Liverpool) Annual Meeting
Contributed Session
Improving Precision by Adjusting for Prognostic Baseline Variables in Randomized Trials with Binary Outcomes, without Regression Model Assumptions
Efstathia Gkioni
2017 (Liverpool) Annual Meeting
Contributed Session
Improving the planning and monitoring of recruitment to clinical trials
Carmen Rosa
2017 (Liverpool) Annual Meeting
Contributed Session
Improving the quality of NIH funded clinical trials
Song Yang
2017 (Liverpool) Annual Meeting
Contributed Session
Improving the testing of treatment effect in clinical trials with time to event outcomes
Dorota Juszczyk
2017 (Liverpool) Annual Meeting
Contributed Session
Incorporating electronic health records data into efficient trial interventions. Cluster randomised trial to reduce antibiotic prescribing in primary care.
Madeleine Hurd
2017 (Liverpool) Annual Meeting
Contributed Session
Increasing follow-up response among parents of very preterm infants: personalised contact, external promotion, and web-based questionnaires
Chris Cook
2017 (Liverpool) Annual Meeting
Contributed Session
Increasing the availability of statistical tools through mobile development
Lucy Bradshaw
2017 (Liverpool) Annual Meeting
Contributed Session
Independent Adjudication of Neonatal Cranial Ultrasound Scans in a Pilot Randomised Trial
Janet Wittes (Moderator)
2017 (Liverpool) Annual Meeting
Educational Session
Independent Data Monitoring Committee Reports: A Practical Guide for Reporting Statisticians
Sally Hopewell
2017 (Liverpool) Annual Meeting
Contributed Session
Influence of peer review on the reporting of primary outcome(s) and statistical analyses of randomised trials
Tao Chen
2017 (Liverpool) Annual Meeting
Contributed Session
Influence of primary outcome change on treatment effect estimates in clinical trials: meta-epidemiological study
Victoria Shepherd
2017 (Liverpool) Annual Meeting
Contributed Session
Informed consent and proxy decision making for research involving adults lacking capacity: a systematic review (framework synthesis)
Claire Rourke
2017 (Liverpool) Annual Meeting
Contributed Session
Informed consent in acute trauma resuscitation: Experiences of a major trauma centre
Matthew Wright
2017 (Liverpool) Annual Meeting
Contributed Session
Informed consent process enhancement approaches for research participants who may be considered vulnerable populations
Kaitlyn Antonelli
2017 (Liverpool) Annual Meeting
Contributed Session
Initial Experience with a Virtual Molecular Tumor Board in a Pragmatic Precision Medicine Study
Nia Goulden
2017 (Liverpool) Annual Meeting
Contributed Session
Integrating continuous stratification variables into a dynamic adaptive randomisation algorithm
Simon Bacon
2017 (Liverpool) Annual Meeting
Contributed Session
Integration of Patients, Caregivers and Healthcare Providers into a Hypertension Management Research Priorities Process
Gareth McCray
2017 (Liverpool) Annual Meeting
Contributed Session
Internal pilot sample size re-estimation in paired comparative diagnostic accuracy trials with a binary response
Jacqueline Hill
2017 (Liverpool) Annual Meeting
Contributed Session
Intervention development and treatment success in randomised controlled trials of rehabilitation
Lucy Bradshaw
2017 (Liverpool) Annual Meeting
Contributed Session
Intra and inter-observer agreement in the interpretation of preterm neonatal cranial ultrasound scans
Brittney Bailey
2017 (Liverpool) Annual Meeting
Contributed Session
Investigating Multiple Imputation in Cluster Randomized Trials
Wei Tan
2017 (Liverpool) Annual Meeting
Contributed Session
Investigating recruitment imbalance in EXPONATE, a cluster randomised trial
Peter Godolphin
2017 (Liverpool) Annual Meeting
Contributed Session
Investigating the effect of independent blinded digital image assessment on the STOP GAP trial
Nada Elbeltagi
2017 (Liverpool) Annual Meeting
Contributed Session
Investigating the impact of phase II trial design parameters on the ability to successfully screen new treatments for phase III trials
Gemma Clayton
2017 (Liverpool) Annual Meeting
Contributed Session
Investigating the use of evidence synthesis in the design and analysis of clinical trials
Leila Rooshenas
2017 (Liverpool) Annual Meeting
Contributed Session
Is it possible to randomise patients to potentially not receive a dressing after surgery? Preliminary findings of the NIHR HTA Bluebelle pilot randomised controlled trial
Helen Myers
2017 (Liverpool) Annual Meeting
Contributed Session
Is there anyone so wise as to learn by the experience of others? Developing and implementing a ‘Lessons Learnt’ database in a Clinical Trials Unit.
Meredith Martyn
2017 (Liverpool) Annual Meeting
Contributed Session
Issues with Over-fitting in Predictive Models Produced for Stratified Medicine: A Case Study on an Ovarian Cancer Trial
Katherine Fairhurst
2017 (Liverpool) Annual Meeting
Contributed Session
Key design features of pilot and feasibility studies to inform successful surgical trials: A systematic analysis of funded studies.
Lisa Reeves
2017 (Liverpool) Annual Meeting
Contributed Session
Keys to Successful Participant Response Rates in a 30 year Longitudinal Study
Emily Graham
2017 (Liverpool) Annual Meeting
Contributed Session
Late stage combination drug development for improved portfolio-level decision-making
J. Jack Lee, Ph.D.
2017 (Liverpool) Annual Meeting
Educational Session
Learning Bayesian Methods and Adaptive Designs: Concepts, Tools, and Applications
Catherine Arundel
2017 (Liverpool) Annual Meeting
Contributed Session
Learning from the OCTET Trial - Exploring acceptability of clinical trials management
Adwoa Hughes-Morley
2017 (Liverpool) Annual Meeting
Contributed Session
Learning lessons from trial decliners about improving recruitment: qualitative study
David Preiss
2017 (Liverpool) Annual Meeting
Contributed Session
LENS – a clinical trial embedded in routine clinical practice to reduce the burden of diabetic eye disease
Rachel Phillips
2017 (Liverpool) Annual Meeting
Contributed Session
Lessons to learn from the reporting of adverse events (AEs) in randomised controlled trials published in high impact journals.
Radhika Kondapaka
2017 (Liverpool) Annual Meeting
Contributed Session
Leveraging Electronic Data Capture (EDC) Systems to Optimize Pharmacovigilance in Clinical Trials
Mansour Sharabiani
2017 (Liverpool) Annual Meeting
Contributed Session
Log-Likelihood is the best correlative measure to estimate the cutpoint for a continuous prognostic variable: A Monte Carlo simulation study
Maiken Pontoppidan
2017 (Liverpool) Annual Meeting
Contributed Session
Long Term Results Of the Incredible Years Parents And Babies Program– A Randomized Controlled Pilot Trial Of A Universal Parenting Intervention In Denmark
Virginia Chiocchia
2017 (Liverpool) Annual Meeting
Contributed Session
Machine perfusion in liver transplantation: practical issues to consider in the design and conduct of a complex multinational interventional trial and the potential impact on the analysis
Paul Whybrow
2017 (Liverpool) Annual Meeting
Contributed Session
Maintaining Recruitment and Informed Consent in the Advanced Stages of a Trial: the By-Band-Sleeve Study
Liz Tremain
2017 (Liverpool) Annual Meeting
Contributed Session
Managed access to NIHR-funded research data: An opportunity for all?
T. Charles Casper
2017 (Liverpool) Annual Meeting
Educational Session
Managing Manuscripts Efficiently in Multicenter Trials
Carlos Diaz-Montana
2017 (Liverpool) Annual Meeting
Contributed Session
Managing our TEMPER: Monitoring triggers and site matching algorithms for defining triggered and control sites in the TEMPER study
Gwenllian Moody
2017 (Liverpool) Annual Meeting
Contributed Session
Managing the challenge of recruiting foster carers into a trial of a supportive group-based social care intervention: lessons learned from the Confidence in Care trial.
James Barrett
2017 (Liverpool) Annual Meeting
Contributed Session
Matching the right patient to the right clinical study: the opportunities for more efficient clinical studies using selective-recruitment designs.
Linda Sharples
2017 (Liverpool) Annual Meeting
Contributed Session
Maximising information in pressure ulcer prevention trials using multi-state modelling
Dr Athene
2017 (Liverpool) Annual Meeting
Contributed Session
Maximising participant retention and outcome data in a long term cancer trial (ProtecT)
Samantha Cruz Rivera
2017 (Liverpool) Annual Meeting
Contributed Session
Maximising research impact: a systematic review of research impact frameworks
Gordon Forbes
2017 (Liverpool) Annual Meeting
Contributed Session
Maximising the relevance of randomised trials to primary care
Lauren Scott
2017 (Liverpool) Annual Meeting
Contributed Session
Maximising trial efficiency in the Airways-2 trial using a multi-functional database
Louise Hiller
2017 (Liverpool) Annual Meeting
Contributed Session
Measurement methods for eliciting opinions on treatment benefits, toxicities and acceptable trade-offs of the two, within the PERSEPHONE trial
Deborah DiLiberto
2017 (Liverpool) Annual Meeting
Contributed Session
Mediation Analysis to Explore Causal Mechanisms in Trials of Complex Interventions
Brent C Opmeer
2017 (Liverpool) Annual Meeting
Educational Session
Methodological and practical considerations in multinational economic evaluation studies
Julia Forman
2017 (Liverpool) Annual Meeting
Contributed Session
Methodological challenges in the REACT Study, a randomized controlled trial of Real Time Continuous Glucose monitoring in Neonatal Intensive Care
Prof Ken Cheung
2017 (Liverpool) Annual Meeting
Invited Session
Methods and Practice of Modern Adaptive Dose Finding Trials: A Progress Report
Iryna Schlackow
2017 (Liverpool) Annual Meeting
Contributed Session
Methods for extrapolation from clinical trial data to inform economic evaluations: a taxonomy
Alice Biggane
2017 (Liverpool) Annual Meeting
Contributed Session
Methods for including patients in core outcome set development
Lucy McParland
2017 (Liverpool) Annual Meeting
Contributed Session
Methods for testing for and handling non-proportional hazards in a Phase II RCT in Chronic Lymphocytic Leukaemia
Polly Scutt
2017 (Liverpool) Annual Meeting
Contributed Session
Methods for training paramedics to recruit patients into the Rapid intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)
Denise Forshaw
2017 (Liverpool) Annual Meeting
Contributed Session
Methods of approaching general practices for trial participant information: feasibility cluster-randomised trial nested within a large multi-centre cluster-randomised controlled cross-over trial
Jane Candlish
2017 (Liverpool) Annual Meeting
Contributed Session
Methods to analyse partially nested randomised controlled trials
Sian Cousins
2017 (Liverpool) Annual Meeting
Contributed Session
Minimising bias in surgical RCTs through blinding: a systematic review
Ken Kelley
2017 (Liverpool) Annual Meeting
Contributed Session
Minimum-risk Point-estimation for the Standardized Mean Difference: A Sequential Estimation Approach
Baptiste Leurent
2017 (Liverpool) Annual Meeting
Contributed Session
Missing data in trial-based cost-effectiveness analysis: a review of the current practice
Ann-Kristin Leuchs, Federal Institute for Drugs and Medical Devices (BfArM), Germany
2017 (Liverpool) Annual Meeting
Invited Session
Missing Outcome Data in Randomized Clinical Trials: addressing the challenges to applying principled methods for analysis of causal estimands
Charlotte Murkin
2017 (Liverpool) Annual Meeting
Contributed Session
Mixed methods feasibility work to inform data collection in a main study: designing case report forms to capture variation in surgical techniques.
Garry Meakin
2017 (Liverpool) Annual Meeting
Contributed Session
Mock activation of a pandemic influenza clinical trial: testing for rapid recruitment
Trudie Lang
2017 (Liverpool) Annual Meeting
Invited Session
Modern methodology to tackle an ancient disease of poverty: Design innovations in tuberculosis clinical trials in resource-poor settings
Jason McCoy
2017 (Liverpool) Annual Meeting
Contributed Session
Monitoring Interactive Response Technology Vendor Implemented Randomization and Dosing Systems
Emily Harrop
2017 (Liverpool) Annual Meeting
Contributed Session
Motives, meanings and misconceptions: exploring the understandings and experiences of advanced lung cancer patients participating in a non-placebo clinical IMP trial
Kerry Hood
2017 (Liverpool) Annual Meeting
Invited Session
MRC Guidance for complex interventions: intervention development and exploratory / feasibility studies
Claire Kerr
2017 (Liverpool) Annual Meeting
Contributed Session
MS SharePoint – Using collaborative software to support collaborative research
Ed Juszczak
2017 (Liverpool) Annual Meeting
Contributed Session
MULTI-ARM PARALLEL GROUP TRIALS – NOT A SIMPLE EXTENSION TO 2-ARM TRIALS
Peter Knapp
2017 (Liverpool) Annual Meeting
Invited Session
Multimedia and digital provision of trial participant recruitment information: opportunities and challenges
Soeun Kim
2017 (Liverpool) Annual Meeting
Contributed Session
Multiple Imputation for Missing Covariates in Clinical Trials with Interactions
Karla DiazOrdaz
2017 (Liverpool) Annual Meeting
Contributed Session
Multiple imputation methods for estimating causal treatment effects in trials with non-compliance
Kimberley Goldsmith
2017 (Liverpool) Annual Meeting
Contributed Session
Multiply efficient trials: combining multiple trial arms and critical secondary questions increases trial efficiency
Gillian Gresham
2017 (Liverpool) Annual Meeting
Contributed Session
Navigating the ClinicalTrials.gov database: A case study
Larisa Tereshchenko
2017 (Liverpool) Annual Meeting
Contributed Session
Network meta-analysis of antiembolic interventions: adjustment for confounders
Catherine Klersy
2017 (Liverpool) Annual Meeting
Contributed Session
Network metanalysis benchmarking the technological development of implantable medical devices
Claire Cochran
2017 (Liverpool) Annual Meeting
Contributed Session
Networked for sucess? The establishment and maturation of a Trainee Reserach Network within a UK based Opthalmology study
Eric Foster
2017 (Liverpool) Annual Meeting
Contributed Session
NeuroNEXT Study Design Working Group Experiences
Sandra Eldridge
2017 (Liverpool) Annual Meeting
Contributed Session
New Cochrane risk of bias tool for cluster randomised tools
Deborah Ashby
2017 (Liverpool) Annual Meeting
Invited Session
New guidance on specifying the target difference (“effect size”) for a RCT
Ceri Rowlands
2017 (Liverpool) Annual Meeting
Contributed Session
New methods for categorising recruitment research: a case study
Phillip Whitehead
2017 (Liverpool) Annual Meeting
Contributed Session
NIHR Clinical Trials Fellowship: Reflections from a fellow and a mentor
Mark Mullee
2017 (Liverpool) Annual Meeting
Contributed Session
NIHR Research Design Service
Jack Wilkinson
2017 (Liverpool) Annual Meeting
Contributed Session
No common denominator: a review of outcome measures in IVF RCTs.
Jessica Kendall
2017 (Liverpool) Annual Meeting
Contributed Session
Non-Stochastic Curtailment in Phase II Oncology Trials
Chi Kin Lam
2017 (Liverpool) Annual Meeting
Contributed Session
Nonparametric Overdose Control for Dose Finding in Drug-Combination Trials
Jennifer Bell
2017 (Liverpool) Annual Meeting
Contributed Session
Observational versus randomised data: Using a fractional factorial RCT to compare results.
Polly Scutt
2017 (Liverpool) Annual Meeting
Contributed Session
Obtaining consent in the pre-hospital setting: consent procedures from the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)
Tolulope Sajobi
2017 (Liverpool) Annual Meeting
Contributed Session
On Synthesis Evidence from Explanatory and Pragmatic trials: A Comparison of Meta-analytic Methods
Gina Simone
2017 (Liverpool) Annual Meeting
Educational Session
One Month, Two Studies, Four FDA Audits
Anna Kearney
2017 (Liverpool) Annual Meeting
Contributed Session
Online resource for Recruitment Research in Clinical triAls research (ORRCA)
Pam Mangat
2017 (Liverpool) Annual Meeting
Contributed Session
Operational Advantages and Challenges with Pragmatic Precision Medicine Trials: The TAPUR Study
Sheila Burgard
2017 (Liverpool) Annual Meeting
Contributed Session
Operationalizing and Testing a Minimization Randomization Algorithm for Use in Clinical Trials
Sheila Burgard
2017 (Liverpool) Annual Meeting
Contributed Session
Operationalizing the Use of Latent Variables in the Process of Determining an ARIC Participant’s Neurocognitive Status at Visit 6
Jeremy Horwood
2017 (Liverpool) Annual Meeting
Contributed Session
Opportunistic trial recruitment during routine primary care consultations for acute conditions: a mixed methods evaluation of recruitment performance and barriers.
Pat Hoddinott
2017 (Liverpool) Annual Meeting
Contributed Session
Opportunities and pitfalls encountered when using the Template for Intervention Description and Replication (TIDieR) to develop a complex intervention to reduce obesity in men.
Karla Hemming
2017 (Liverpool) Annual Meeting
Invited Session
Optimality in stepped wedge cluster randomised trials – when and where to take measurements
Alison Deary
2017 (Liverpool) Annual Meeting
Contributed Session
Optimising primary outcome data collection in a neonatal trial
Warwick Medical School
2017 (Liverpool) Annual Meeting
Educational Session
Optimising setup and recruitment of multicentre complex randomised control trials
Talia Isaacs
2017 (Liverpool) Annual Meeting
Contributed Session
Optimising the recruitment of underrepresented ethnic minority patients to telehealth diabetes trials: Examining the role of language and research reporting practices
Martina Svobodova
2017 (Liverpool) Annual Meeting
Contributed Session
Optimising trial recruitment with well-designed screening log: experiences from the ROCS Study
Rui (Sammi) Tang
2017 (Liverpool) Annual Meeting
Invited Session
Optimizing Clinical Trials by Using Historical Data and Novel Designs
Catherine Dillon
2017 (Liverpool) Annual Meeting
Invited Session
Optimizing Quality in Clinical Research: Strategies for Preventing Errors in Trial Operation, Study Data, and Human Subjects Protection
Caroline Main
2017 (Liverpool) Annual Meeting
Contributed Session
Outcome measurement in paediatric proton beam radiation therapy studies: is greater standardisation needed?
junhua zhang
2017 (Liverpool) Annual Meeting
Contributed Session
Outcome Measures in Clinical trials of traditional Chinese medicine for stable angina pectoris
Paula Williamson
2017 (Liverpool) Annual Meeting
Contributed Session
Outcome selection in clinical trials – looking back at the problems and moving forward with solutions
Julius Sim
2017 (Liverpool) Annual Meeting
Contributed Session
Outcome-adaptive randomization: some ethical issues
Mike Clarke (invited)
2017 (Liverpool) Annual Meeting
Invited Session
Outcomes in Trials and Systematic Reviews: Why we should be paying more attention
Amy Ruppert
2017 (Liverpool) Annual Meeting
Contributed Session
Overall Success Rate of a Safe and Efficacious Drug: Results Using Six Phase I Designs, Each Followed by Phase II and III Trials Using Standard Designs
Jennie Young
2017 (Liverpool) Annual Meeting
Contributed Session
Overtreatment of DCIS – 4 years on from the Marmot Review - Progress with the LORIS Trial
Rachel Phillips
2017 (Liverpool) Annual Meeting
Contributed Session
Overview of statistical methods to monitor harms during the conduct of a randomised controlled trial
Claire Vale
2017 (Liverpool) Annual Meeting
Contributed Session
Participant involvement as a form of patient and public involvement in clinical trials: experience, reflections and recommendations
RANI JAYSWAL
2017 (Liverpool) Annual Meeting
Contributed Session
Partnership of Cancer Center Core Facilities with Community-Based Research Networks in the Coordination and Management of Multi-Center Clinical Trials
Cushla Cooper
2017 (Liverpool) Annual Meeting
Contributed Session
Patient and public involvement into the design of a Paediatric surgical trial: The NINJA study
Lucy Selman
2017 (Liverpool) Annual Meeting
Contributed Session
Patient and Public Involvement: An Investigation
prof. Kit Roes
2017 (Liverpool) Annual Meeting
Invited Session
Patient centered outcome measurements in rare disease trials: Challenges and potential solutions
Emily Holmes
2017 (Liverpool) Annual Meeting
Contributed Session
Patient preferences for outcomes in clinical trials: implications for medicines optimisation
Rachel McNamara
2017 (Liverpool) Annual Meeting
Contributed Session
Patient reported outcome measure development in epilepsy and intellectual disability: A systematic review of measures of anti-epileptic drug side effects
Colin Ridyard
2017 (Liverpool) Annual Meeting
Contributed Session
Patient-level information and costing systems (PLICS) as a source of routinely collected cost data for trial-based economic evaluations
Annmarie Nelson
2017 (Liverpool) Annual Meeting
Contributed Session
Patients’ experience in adaptive oncology clinical trials: Trial acceptability, feasibility, efficiency, processes and outcomes
Rachel Maishman
2017 (Liverpool) Annual Meeting
Contributed Session
Patterns of adverse events after cardiac surgery
Heidi Gardner
2017 (Liverpool) Annual Meeting
Contributed Session
Perceptions and experiences of participant recruitment: A qualitative interview study with trial stakeholders
Emily OBrien
2017 (Liverpool) Annual Meeting
Contributed Session
Perceptions of the Utility and Barriers of Using Electronic Health Records for Patient Screening in Clinical Trials: An In-Depth Interviews Study of Site Coordinators
Roy Elbers
2017 (Liverpool) Annual Meeting
Contributed Session
Performance bias in trials that cannot blind participants and healthcare providers to assigned interventions: implications for trial conduct
Alexia Iasonos
2017 (Liverpool) Annual Meeting
Invited Session
Phase 2 Basket Trial Designs and Applications
Deirdre Hurley
2017 (Liverpool) Annual Meeting
Contributed Session
Physiotherapists’ views of the acceptability and feasibility of the Self-management of Osteoarthritis and Low back pain through Activity and Skills (SOLAS) complex intervention within a cluster randomised controlled feasibility trial [ISRCTN 49875385]
Amparo Casanova
2017 (Liverpool) Annual Meeting
Contributed Session
PILOT AND FEASIBILITY STUDIES: A SYSTEMATIC REVIEW OF STUDIES CONDUCTED AT THE POPULATION HEALTH RESEARCH INSTITUTE
Lawrence Richer
2017 (Liverpool) Annual Meeting
Contributed Session
Placebo response is not decreased by enrichment trial designs in randomized controlled trials of triptan medications in the paediatric age group
Naomi Merritt
2017 (Liverpool) Annual Meeting
Contributed Session
Placebo Surgery Trials in the NHS are Possible
Indrani Bhattacharya
2017 (Liverpool) Annual Meeting
Contributed Session
Planned implementation of a study within a trial using a stepped wedge trial design evaluating the introduction of a patient decision aid on decisional conflict in patients’ considering entry into the PRIMETIME study
Kukatharmini Tharmaratnam
2017 (Liverpool) Annual Meeting
Contributed Session
Point and interval estimation for predicting individual patients treatment effect based on randomized clinical trial data
Barbara E. Bierer, MD
2017 (Liverpool) Annual Meeting
Invited Session
Post trial access to Investigational Medicines: Policy and Practical Recommendations
Rebecca Llewellyn-Bennett
2017 (Liverpool) Annual Meeting
Contributed Session
Post-trial follow-up methodology in large randomized controlled trials: a systematic review
Naoki Ishizuka
2017 (Liverpool) Annual Meeting
Contributed Session
Practical sample size re-estimation of propensity score analysis for prospective study.
Sharon Ruddock
2017 (Liverpool) Annual Meeting
Contributed Session
Practicalities of obtaining long term follow up data from International Sites
Sian Taylor-Phillips
2017 (Liverpool) Annual Meeting
Contributed Session
Pragmatic Integrated Randomised Controlled Trials in Screening: Experience from a trial in 1.2million women attending breast screening
Brian Egleston
2017 (Liverpool) Annual Meeting
Contributed Session
Pragmatic verification of cancer clinical trial efficacy findings using the Surveillance Epidemiology and End Results (SEER) database
Kirsty Loudon
2017 (Liverpool) Annual Meeting
Educational Session
PRECIS-2 PRECIS-2: Precisely how can this tool help investigators design trials to achieve practical answers to “real world” questions?
Dr Andrea Jorgensen
2017 (Liverpool) Annual Meeting
Invited Session
Precision medicine – addressing the key challenges of demonstrating clinical utility
Karan Vadher
2017 (Liverpool) Annual Meeting
Contributed Session
Prediction model for developmental outcome at 2 years of age for babies born very preterm
Wendi Qian
2017 (Liverpool) Annual Meeting
Contributed Session
Predictive power in feasibility study design: implementation in the INTERIM melanoma cancer trial
Peter Knapp
2017 (Liverpool) Annual Meeting
Contributed Session
Preliminary analysis of a new measure of quality of patient decision making about research participation
Tamara Haller
2017 (Liverpool) Annual Meeting
Contributed Session
Presentation and Publication System (PnP): A tool to facilitate efficient tracking and reporting of the presentation and publication process
Kerry Woolfall
2017 (Liverpool) Annual Meeting
Contributed Session
Priorities for methodological research on patient and public involvement in clinical trials: a modified Delphi process
Healy Patricia
2017 (Liverpool) Annual Meeting
Contributed Session
PRioritising Recruitment in Randomised Trials: The PRioRiTy Study- An Ireland and UK priority setting partnership
Sarah Gorst
2017 (Liverpool) Annual Meeting
Contributed Session
Priority setting for core outcome set development
Jamie Murdoch
2017 (Liverpool) Annual Meeting
Contributed Session
Process evaluation for the PREPARE-ABC study: context mapping, pinchpoints and implications for implementation and theoretical fidelity.
William Stevens
2017 (Liverpool) Annual Meeting
Contributed Session
Producing CDISC compliant data and metadata for regulatory submissions
Clare Cruickshank
2017 (Liverpool) Annual Meeting
Contributed Session
Quality assurance (QA) challenges in the development of international trials in rare diseases.
Noga Lewin
2017 (Liverpool) Annual Meeting
Contributed Session
Quality Control of SDTM Domain Mappings from Electronic Case Report Forms
Joanne Rothwell
2017 (Liverpool) Annual Meeting
Contributed Session
Quantifying Effect Sizes in Clinical Trials
Heather Catt
2017 (Liverpool) Annual Meeting
Contributed Session
Quantitative benefit-risk modelling of infliximab biosimilar Inflectra versus reference product Remicade in the treatment of Crohn’s disease
Simon Bond
2017 (Liverpool) Annual Meeting
Contributed Session
R package to implement Rank Preserving Structural Failure Time Models
Rebecca Randell
2017 (Liverpool) Annual Meeting
Contributed Session
Randomised Controlled Trials and Realist Evaluation: In What Contexts and How?
Jeff Szychowski
2017 (Liverpool) Annual Meeting
Contributed Session
Randomization Balance in Multicenter Clinical Trials with Short Drug Life and Rapid Allocation
Gene Pennello
2017 (Liverpool) Annual Meeting
Contributed Session
Randomized Trial Designs for Evaluating Predictive Markers: What is the Estimand?
Lisa Woodhouse
2017 (Liverpool) Annual Meeting
Contributed Session
Rationale for using an ordinal primary outcome in clinical trials for the prevention of recurrent stroke and transient ischaemic attack
Jane Daniels
2017 (Liverpool) Annual Meeting
Contributed Session
Reaching a consensus on causes of pain: use of an expert independent panel to determine a reference standard
Qi Long
2017 (Liverpool) Annual Meeting
Invited Session
Recent Advances in Methods for Handling Missing Data in Clinical Trials
Karla Hemming
2017 (Liverpool) Annual Meeting
Invited Session
Recent Developments in the Design and Analysis of Cluster Randomized Trials
Suzanne Breeman
2017 (Liverpool) Annual Meeting
Contributed Session
Record Linkage of Trial Datasets to Hospital Admission Records: A Trial Manager’s Experience
Steven Penegar
2017 (Liverpool) Annual Meeting
Contributed Session
Recruitment aids for a phase II randomised trial in low risk bladder cancer
Claire Diver
2017 (Liverpool) Annual Meeting
Contributed Session
Recruitment and participation in the stem cell trial of recovery enhancement-3 (STEMS-3): experiences of stroke survivors and their carer’s.
Stephen Walters
2017 (Liverpool) Annual Meeting
Contributed Session
Recruitment and retention of participants in randomised controlled trials: a review of trials funded by the United Kingdom Health Technology Assessment Programme
Christy Toms
2017 (Liverpool) Annual Meeting
Contributed Session
Recruitment estimates provided by sites - are they consistent with observed accrual?
Sarah Tearne
2017 (Liverpool) Annual Meeting
Contributed Session
Recruitment in GP practices: Research assistant or research nurse?
Katie Flaherty
2017 (Liverpool) Annual Meeting
Contributed Session
Recruitment monitoring and predictions: data from the Tranexamic acid for IntraCerebral Haemorrhage (TICH-2) trial.
Ceri Rowlands
2017 (Liverpool) Annual Meeting
Contributed Session
Recruitment to randomised controlled trials in patients receiving unplanned hospital care: a systematic review and in-depth analysis using the ORRCA database
Anna Kearney
2017 (Liverpool) Annual Meeting
Contributed Session
Reducing attrition: The communication of retention and withdrawal within Patient Information Sheets
Alexanda Wright-Hughes
2017 (Liverpool) Annual Meeting
Contributed Session
Reducing bias in randomised controlled trials involving therapists: To randomise or not to randomise – what are the questions?
Jamilla Hussain
2017 (Liverpool) Annual Meeting
Contributed Session
Reducing missing data in palliative care randomised controlled trials: a mixed-methods study
Jennifer Talton
2017 (Liverpool) Annual Meeting
Contributed Session
REDUCING UNDER- AND OVER-TRIAGE IN MOTOR VEHICLE CRASHES USING AN INJURY-BASED APPROACH
Prof Marion Campbell
2017 (Liverpool) Annual Meeting
Invited Session
REGISTRY-BASED RANDOMISED CONTROLLED TRIALS – THE FUTURE FOR CLINICAL TRIALS?
Catherine Oldenburg
2017 (Liverpool) Annual Meeting
Contributed Session
Regression discontinuity for replication of randomized controlled trial results: An application to the Mycotic Ulcer Treatment Trials
Sara Valencia
2017 (Liverpool) Annual Meeting
Contributed Session
Regulation in Latin America and its impact on the execution of multinational clinical trials to evaluate vaccines.
Jane Blazeby
2017 (Liverpool) Annual Meeting
Contributed Session
REPORT-UK (Real-time Electronic Patient Outcome ReporTing of adverse events in UK cancer trials): Methods to optimise data collection
Anna Kearney
2017 (Liverpool) Annual Meeting
Contributed Session
Reported reasons for missing data
Marcus Johnson
2017 (Liverpool) Annual Meeting
Contributed Session
Research Site Mentoring: A Novel Approach to Improving Study Recruitment
Alina Striha
2017 (Liverpool) Annual Meeting
Contributed Session
Response and Progression Endpoint Review in a Large Phase III Randomised Control Trial of Multiple Myeloma
Katie Gillies
2017 (Liverpool) Annual Meeting
Contributed Session
Retention in randomised trials: What matters to Trial Managers?
Cathryn Rankin
2017 (Liverpool) Annual Meeting
Contributed Session
Retrospective Preparation of Trial Results for Regulatory Submission: Challenges and Lessons Learned
Nicola Totton
2017 (Liverpool) Annual Meeting
Contributed Session
Review of pilot and feasibility studies from a registry website; an overview of recent practice.
Jody Ciolino
2017 (Liverpool) Annual Meeting
Contributed Session
Review of Treatment Allocation Schemes Reported in Published Clinical Trial Results
Caroline Hurley
2017 (Liverpool) Annual Meeting
Contributed Session
RISK BASED MONITORING (RBM) TOOLS FOR CLINICAL TRIALS: A SYSTEMATIC REVIEW
Vicky Tsipouri
2017 (Liverpool) Annual Meeting
Contributed Session
Rituximab versus cyclophosphamide for the treatment of connective tissue disease associated interstitial lung disease (RECITAL): a randomised controlled trial.
Tianchen Qian
2017 (Liverpool) Annual Meeting
Contributed Session
Robust Methods for Improving Power in Group Sequential Randomized Trial Designs, by Leveraging Prognostic Baseline Variables and Short-term Outcomes
Daniel Sabanes Bove
2017 (Liverpool) Annual Meeting
Contributed Session
Rolling dose escalation with overdose control: an efficient and safe phase 1 design
James Moon
2017 (Liverpool) Annual Meeting
Contributed Session
S0819: Lessons Learned from Conduct of a Cooperative Group Phase III Trial with a Biomarker Defined Subset Co-Primary Objective.
Dominic Stringer
2017 (Liverpool) Annual Meeting
Contributed Session
Sample size adaptations in a randomised controlled biomarker based strategy (hybrid) trial: Experience from the OuTSMART Trial.
Andrew Forbes
2017 (Liverpool) Annual Meeting
Contributed Session
Sample size calculations for cluster randomised trials: Reconciling variance components in generalised linear mixed models with marginal intracluster correlations
Duncan Wilson
2017 (Liverpool) Annual Meeting
Contributed Session
Sample size calculations using Bayesian optimisation
Julie Wych
2017 (Liverpool) Annual Meeting
Contributed Session
Sample Size Re-estimation in Cross-over Trials: a Simulation Study Investigating the Type I Error, Power and Sample Size in the AIM HY-INFORM Study
Kenneth Babigumira
2017 (Liverpool) Annual Meeting
Contributed Session
SCALING THE DRUG SUPPLY MANAGEMENT MOUNTAIN: A CASE STUDY OF THE ADD-ASPIRIN TRIAL
Vivien Coates
2017 (Liverpool) Annual Meeting
Contributed Session
Scaling Up? Lessons from a feasibility study involving people with type 2 diabetes and their families
Helen Myers
2017 (Liverpool) Annual Meeting
Contributed Session
Seeing the light at the end of the carpal tunnel: The challenges of recruiting sites to a Clinical Trial of an Investigational Medicinal Product in primary care.
Monica Taljaard
2017 (Liverpool) Annual Meeting
Invited Session
Selection biases in cluster randomised trials: how do identify, avoid and report
Matthew Franklin
2017 (Liverpool) Annual Meeting
Contributed Session
Self-reported and electronic resource use for trial-based economic evaluations: the current state of play in England and considerations for the future
Holly Tovey
2017 (Liverpool) Annual Meeting
Contributed Session
Sensitivity analysis assessing the impact of patient self-reported follow up in the REACT trial
Suzie Cro
2017 (Liverpool) Annual Meeting
Contributed Session
Sensitivity analysis for missing data using the Delta method: the impact of incorporating a prior distribution on Delta
Steff Lewis
2017 (Liverpool) Annual Meeting
Invited Session
Sharing individual participant data from clinical trials: Current practice and future thinking
Jamilla Hussain
2017 (Liverpool) Annual Meeting
Contributed Session
Should CONSORT do more to improve the quality of missing data reporting in trials?
Zhibao Mi
2017 (Liverpool) Annual Meeting
Contributed Session
Simulation of Various Strategies for Optimal Selection of Randomization Methods in Multicenter Clinical Trials
Giuseppe de Vito
2017 (Liverpool) Annual Meeting
Contributed Session
Single Agent Trastuzumab or Lapatinib to Treat HER2-Overexpressing Breast Cancer: combining past and current evidence in a Bayesian reanalysis.
Kerry Woolfall
2017 (Liverpool) Annual Meeting
Contributed Session
Site training to improve healthcare practitioners’ confidence in recruiting to a challenging critical care trial
Clemence Leyrat
2017 (Liverpool) Annual Meeting
Contributed Session
Small sample corrections for cluster randomised trials: implications for power and type I error rate
Vichithranie Madurasinghe
2017 (Liverpool) Annual Meeting
Contributed Session
Smoking treatment optimisation in pharmacies (STOP): cluster randomised pilot trial of a training intervention
Joy Black
2017 (Liverpool) Annual Meeting
Contributed Session
Splintered Adverse Event Reporting in Multicenter Clinical Trials
Beatriz Goulao
2017 (Liverpool) Annual Meeting
Contributed Session
Split-plot designs: sample size considerations
David White
2017 (Liverpool) Annual Meeting
Contributed Session
Staff experiences of closing out a clinical trial involving withdrawal of treatment: qualitative study
Guy Peryer
2017 (Liverpool) Annual Meeting
Contributed Session
Standard operating procedures for managing adverse events in trials that do not involve an investigational medicinal product: a protocol for a Delphi consensus study
Alice Tsai
2017 (Liverpool) Annual Meeting
Contributed Session
STANDARDISATION AND COMPETENCY ASSESSMENT OF TRANSANAL TOTAL MESORECTAL EXCISION (TATME) FOR RECTAL CANCERS: SURGICAL QUALITY ASSURANCE IN THE CONTEXT OF A RANDOMISED CONTROLLED TRIAL
Susanna Dodd
2017 (Liverpool) Annual Meeting
Contributed Session
Standardised taxonomy for the classification of trial outcomes within core outcome sets and Cochrane Reviews
Cliona McDowell
2017 (Liverpool) Annual Meeting
Contributed Session
Statistical Analysis Plans for Internal Pilots in Randomised Controlled Trials
Amylou Dueck
2017 (Liverpool) Annual Meeting
Contributed Session
Statistical analysis strategies for PRO-CTCAE data in oncology clinical trials: a simulation study
David Gillespie
2017 (Liverpool) Annual Meeting
Contributed Session
Statistical and Practical Considerations when Measuring Adherence to Medication in Clinical Trials: Estimation of Agreement, Prediction of Disagreement, and Derivation of Calibrated Measures
Theodore Karrison
2017 (Liverpool) Annual Meeting
Invited Session
Statistical and Practical Considerations When Terminating a Trial Early: Contrasting early stopping due to harm (ACCORD) versus for benefit (SPRINT).
Shun Fu Lee
2017 (Liverpool) Annual Meeting
Contributed Session
Statistical considerations for analyzing multiplex biomarker data from prospective studies.
Lee Middleton
2017 (Liverpool) Annual Meeting
Contributed Session
Statistical issues in data monitoring of clinical trials that incorporate assessment of pregnancy loss
Mohamed Mubasher
2017 (Liverpool) Annual Meeting
Contributed Session
Stopping Rules for Long Term Clinical Trials Based on Two Consecutive Rejections of the Null Hypothesis
Heidi Gardner
2017 (Liverpool) Annual Meeting
Contributed Session
Strategies to improve participant recruitment to randomised controlled trials: A systematic review of non-randomised evaluations
Eleanor Mitchell
2017 (Liverpool) Annual Meeting
Contributed Session
Streamlining SAE handling in a busy CTU
Colin Everett
2017 (Liverpool) Annual Meeting
Contributed Session
Structured Statistical Analysis Plans for improved clarity of intended analysis
Barnaby Reeves
2017 (Liverpool) Annual Meeting
Contributed Session
Success of randomizing trial participants to disclosure of allocation early or late: a methodological study to investigate performance bias
Amy Rogers
2017 (Liverpool) Annual Meeting
Contributed Session
Successful Recruitment to a Large Online Randomised Trial: The TIME study
Jared Foster
2017 (Liverpool) Annual Meeting
Contributed Session
Surrogate Endpoint Evaluation in a Personalized Medicine Framework
Eileen Stock
2017 (Liverpool) Annual Meeting
Contributed Session
Surveillance of Clinical Trial Performance using Centralized Statistical Monitoring
Kathryn Monson
2017 (Liverpool) Annual Meeting
Contributed Session
Surveying patients’ views on trial information provision and decision making using the ‘Accept/Decline’ clinical trials questionnaire
Jieling Miao
2017 (Liverpool) Annual Meeting
Contributed Session
SWOG S1700: An institutional cluster-randomized trial of a surgical lymph node specimen collection kit in the Cooperative Group Setting
Ikhlaaq Ahmed
2017 (Liverpool) Annual Meeting
Contributed Session
Synchronous Chemo-Radiation Can Reduce Local and Loco-regional Recurrence In Early Stage Breast Cancer: Results of a randomised controlled trial SECRAB
Gordon Forbes
2017 (Liverpool) Annual Meeting
Contributed Session
Systematic review of the use of mediation analysis in randomised controlled trials in the primary healthcare setting
Lauren Yesko
2017 (Liverpool) Annual Meeting
Contributed Session
Tailoring a Comprehensive Website to Support a Clinical Research Network
Allan Walker
2017 (Liverpool) Annual Meeting
Contributed Session
Taking the REDCap data management tool to the next step. Reducing complexity in study design by smoother integration of external randomisation services thus providing a more streamlined experience for users
Fang Chen
2017 (Liverpool) Annual Meeting
Contributed Session
Telephone support for mail based recruitment and follow-up in a large randomized trial
Dionne Russell
2017 (Liverpool) Annual Meeting
Contributed Session
The advantages of simple analytics in ePRO environments
Dr Hemming
2017 (Liverpool) Annual Meeting
Contributed Session
The assumption of common secular trends across clusters in a stepped-wedge cluster randomised trial: does it matter?
Gavin Reilly
2017 (Liverpool) Annual Meeting
Contributed Session
The changing world of clinical trials 2003 – 2017: A view from the AspECT trial
Sarah Gaussoin
2017 (Liverpool) Annual Meeting
Contributed Session
The Cocoa Supplement and Multivitamin Outcomes Study in the Mind (COSMOS-MIND): Design and Rationale
David Reeves
2017 (Liverpool) Annual Meeting
Contributed Session
The Cohort Multiple Randomised Controlled Trial: methodological lessons from a practical application (the PROTECTS trial)
minjin kang
2017 (Liverpool) Annual Meeting
Contributed Session
The comparison of results from Nested case-control and Nested cohort design in Big Data
Scott Rushing
2017 (Liverpool) Annual Meeting
Contributed Session
The COMPASS Study - Dynamic Generation of Patient-specific eCare Plans in a Pragmatic Trial
Paul Silcocks
2017 (Liverpool) Annual Meeting
Contributed Session
The design and analysis of early phase II trials with naturally bounded continuous fractional outcomes
Kirsty Cockle
2017 (Liverpool) Annual Meeting
Contributed Session
The EAGLE Study: Improving the Wellbeing of Men by Evaluating and Addressing the Gastrointestinal Late Effects of Radical Treatment for Prostate Cancer
Alison Pullan
2017 (Liverpool) Annual Meeting
Contributed Session
The effect of small or unbalanced clusters of patients on logistic regression models in surgical trials
Simon Bacon
2017 (Liverpool) Annual Meeting
Contributed Session
The Effect of the Non-Pharmacological Extension of CONSORT in Quality of Reporting of Behavioural weight loss RCTs
Jonathan Gibb
2017 (Liverpool) Annual Meeting
Contributed Session
The evil of eval() in CTMS - How to get more from user defined code
Andisheh Bakhshi
2017 (Liverpool) Annual Meeting
Contributed Session
The Glasgow ‘Deep End’ Links Worker Programme Evaluation: Analysis Implication of an Unusual Randomised Study Design
Christopher Partlett
2017 (Liverpool) Annual Meeting
Contributed Session
The impact of blinded endpoint review on the incidence of primary short-term outcomes in the SIFT trial
Kaleab Abebe
2017 (Liverpool) Annual Meeting
Contributed Session
The Impact of Sample Size Re-estimation using Baseline ICC in Cluster Randomized Trials: 3 Case Studies
Karen Innes
2017 (Liverpool) Annual Meeting
Contributed Session
The importance of informational items in a Randomised Controlled Trial Participant Information Leaflet: A mixed method study
Ian Thomas
2017 (Liverpool) Annual Meeting
Contributed Session
The importance of randomisation in evaluation of treatments for Acute Myeloid Leukaemia: Lessons from the UK NCRI AML16 and LI-1 trials
Laura Howells
2017 (Liverpool) Annual Meeting
Contributed Session
The minimum clinically important difference (MCID) of the Patient Oriented Eczema Measure (POEM): do different methods of calculation give different MCIDs?
Jody Ciolino
2017 (Liverpool) Annual Meeting
Contributed Session
The Mothers and Babies Cluster-Randomized Trial: A Complex Case of Constrained Randomization
Julia Robertson
2017 (Liverpool) Annual Meeting
Contributed Session
The Paperless Paradigm: Transitioning to Direct Participant Data Entry in the SEARCH for Diabetes in Youth Study
Robert Hills
2017 (Liverpool) Annual Meeting
Contributed Session
The Patient Journey Planner: An integrated approach to trials of targeted therapies with application to cancer and haematological malignancies
Steven A. Julious
2017 (Liverpool) Annual Meeting
Invited Session
The PLEASANT Trial – practical experiences and lessons for a primary care cluster randomised trial looking to prevent the peak in asthma after the return to school analysed using routine data
Nicky Welton
2017 (Liverpool) Annual Meeting
Contributed Session
The potential benefit of an RCT comparing wound dressings in general surgery (the Bluebelle study): a Value of Information analysis and comparison with standard sample size calculations
Sandra Eldridge
2017 (Liverpool) Annual Meeting
Invited Session
The Pragmatic Randomized Controlled Trial at 50: Past Successes; Future Challenges
Sue Bell
2017 (Liverpool) Annual Meeting
Contributed Session
The pros and cons of an ‘umbrella’ trial design for a rare disease from a trial management and data management perspective
Claire Chan
2017 (Liverpool) Annual Meeting
Contributed Session
The Quality of Reporting of Pilot and Feasibility Cluster Randomised Trials: A Systematic Review
Helen Myers
2017 (Liverpool) Annual Meeting
Contributed Session
The role and impact of patient and public involvement and engagement (PPIE) in clinical research: perspectives from Keele CTU Project Management.
Lee Beresford
2017 (Liverpool) Annual Meeting
Contributed Session
The SALVO Study: A Retrospective Take on an Interim Analysis of Futility in a Randomised Trial
Aiden Doherty on behalf of the Clinical Trials Transformation Initiative Mobile Clinical Trials Program
2017 (Liverpool) Annual Meeting
Invited Session
The Scientific and Technological Issues Surrounding the use of Mobile Devices in Clinical Trials: A Clinical Trials Transformation Initiative (CTTI) Project
Tracee Williams
2017 (Liverpool) Annual Meeting
Contributed Session
The Training Documentation Form – Going Beyond the Basics for the National Institute on Drug Abuse (NIDA) National Drug Abuse Treatment Clinical Trials Network (CTN)
Matthew Parkes
2017 (Liverpool) Annual Meeting
Contributed Session
The Two-Stage Treatment Selection (TSTS) Design: A Novel Approach to Treatment Selection in Clinical Trials
Judith Bliss
2017 (Liverpool) Annual Meeting
Contributed Session
The UK plasma based Molecular profiling of Advanced breast cancer to inform Therapeutic CHoices (plasmaMATCH) Trial: A multiple parallel cohort, open-label, multi-centre phase IIa clinical trial aiming to provide proof of principle efficacy for designated targeted therapies in patients with advanced breast cancer where the targetable mutation is identified through ctDNA screening (CRUK/15/010)
Sharon Kean
2017 (Liverpool) Annual Meeting
Contributed Session
The UKCRC Information Systems Operational Group: What is it we do?
Caroline Kristunas
2017 (Liverpool) Annual Meeting
Contributed Session
The use of feasibility studies for stepped-wedge cluster randomised trials: a review of impact and scope.
Reuben Ogollah
2017 (Liverpool) Annual Meeting
Contributed Session
The use of regular text messaging over one year to collect primary outcome data in a randomised controlled trial
Richard Jackson
2017 (Liverpool) Annual Meeting
Contributed Session
The use of unequal allocation ratios in the design of randomised Phase II trials
Francesca Schiavone
2017 (Liverpool) Annual Meeting
Contributed Session
This is a platform alteration: A Trial Management Perspective on the operational aspects of adaptive platform trials
David Pickles
2017 (Liverpool) Annual Meeting
Contributed Session
Time well spent? A comparison of the work associated with collecting primary and secondary outcomes
Jayne Tierney
2017 (Liverpool) Annual Meeting
Contributed Session
Timely and reliable evaluation of the effects of interventions: a Framework for Adaptive Meta-analysis (FAME)
Jules Hernandez-Sanchez
2017 (Liverpool) Annual Meeting
Contributed Session
Tocilizumab in pulmonary hypertension
Jenna Gabrio
2017 (Liverpool) Annual Meeting
Contributed Session
Tools and Processes for Tracking IRB Approvals as a DCC for Large Multi-Center Clinical Research Networks
Michael Ham
2017 (Liverpool) Annual Meeting
Contributed Session
TRACKING DATA REQUESTS FROM INITIATION TO PUBLICATION THROUGH THE USE OF A WEB-ENABLED DATABASE SYSTEM.
Abigail Shoben
2017 (Liverpool) Annual Meeting
Contributed Session
Tradeoffs of a randomize, then consent approach to improving cluster participation rates in cluster randomize trials
Natalie Ives
2017 (Liverpool) Annual Meeting
Contributed Session
Training the Clinical Investigators of the Future – A Clinical Trials Clerkship
Jye-Yu Backlund
2017 (Liverpool) Annual Meeting
Contributed Session
Transition from Paper to Digital Electrocardiograms (ECGs) after 30 Years of Follow-up in the DCCT/EDIC Study
Courtney Nelson
2017 (Liverpool) Annual Meeting
Contributed Session
Translation of a single-center cellular therapy manufacturing approach to a multi-center, center-specific manufacturing platform: the experience of the Blood and Marrow Transplant Clinical Trials Network (BMT CTN) Protocol #1401.
Lucy Beasant
2017 (Liverpool) Annual Meeting
Contributed Session
Treatment preference and recruitment to a paediatric randomised controlled trial: Managed Activity Graded Exercise iN Teenagers and pre-Adolescents (MAGENTA).
Victoria Goodwin
2017 (Liverpool) Annual Meeting
Contributed Session
Treatment success in randomised controlled trials of rehabilitation: a review
Susan Halabi
2017 (Liverpool) Annual Meeting
Contributed Session
Two New Residuals In Survival Analysis With Full Likelihood
Dr. Richéal Burns
2017 (Liverpool) Annual Meeting
Educational Session
Understanding and interpreting health economic evaluation alongside clinical trials.
Professor Richard Emsley
2017 (Liverpool) Annual Meeting
Educational Session
Understanding how treatments work: Evaluating treatment mechanisms in randomised trials
Zoe Tolkien
2017 (Liverpool) Annual Meeting
Contributed Session
Understanding methods for the assessment of patient adherence: a case study in removable devices for the improvement of trial outcome data.
Karla DiazOrdaz
2017 (Liverpool) Annual Meeting
Contributed Session
Understanding, quantifying and reducing recruitment bias in cluster randomized trials
Oxford Clinical Trials Research Unit, Centre for Statistics in Medicine
2017 (Liverpool) Annual Meeting
Educational Session
Understanding, reporting and conducting pilot and feasibility trials
Assaf Oron
2017 (Liverpool) Annual Meeting
Contributed Session
Up-and-Down Designs Enhanced with SPRT Rules for Phase I Cancer Trials
Assaf P. Oron
2017 (Liverpool) Annual Meeting
Educational Session
Up-and-Down: The Forgotten Alternative for Phase I Trials
Barbara Braffett
2017 (Liverpool) Annual Meeting
Contributed Session
Use of a Non-Diabetic Spouse Control Group in the DCCT/EDIC Hearing Study
Leona Batten
2017 (Liverpool) Annual Meeting
Contributed Session
Use of data review software for data management
Katie Pike
2017 (Liverpool) Annual Meeting
Contributed Session
Use of instrumental variables within randomised controlled trials
Francesca Fiorentino
2017 (Liverpool) Annual Meeting
Contributed Session
Use of longitudinal data in the analysis of biomarkers: lessons from simulation and reality.
Elaine Pascoe
2017 (Liverpool) Annual Meeting
Contributed Session
Use of minimization in multi-center clinical trials - when to not add randomization
Clare Thomas
2017 (Liverpool) Annual Meeting
Contributed Session
Use of primary care electronic records to monitor and improve intervention delivery of a GP practice level intervention.
Olympia Papachristofi
2017 (Liverpool) Annual Meeting
Contributed Session
Use of routine databases to aid the design of multicentre surgical trials with length-of-stay as the primary outcome.
Nuria Porta
2017 (Liverpool) Annual Meeting
Contributed Session
Use of simulations to explore recruitment and the impact of late availability of experimental arms in the PIVOTALboost trial
Torsak Bunupuradah
2017 (Liverpool) Annual Meeting
Contributed Session
Usefulness of in-house electronic health record and task-shifting in a pediatric HIV cohort, Bangkok, Thailand
Royes Joseph
2017 (Liverpool) Annual Meeting
Contributed Session
Using “off-treatment” data to estimate the de facto estimand in a randomised trial
Daniel Hind
2017 (Liverpool) Annual Meeting
Contributed Session
Using a logic model and a triangulation protocol for integrating quantitative and qualitative research data in a mixed-methods feasibility study incorporating an external pilot RCT
Stephanie DuBose
2017 (Liverpool) Annual Meeting
Contributed Session
USING A PATIENT REGISTRY TO CONDUCT NON-CLINIC ENGAGED STUDIES
Elizabeth Turner
2017 (Liverpool) Annual Meeting
Contributed Session
Using causal diagrams to guide analyses of randomized controlled trials with missing outcomes
Erik Doffagne
2017 (Liverpool) Annual Meeting
Contributed Session
Using Central Statistical Monitoring to Drive Quality into Clinical Trials
Michelle Nunn
2017 (Liverpool) Annual Meeting
Contributed Session
Using dedicated study laptops to enhance data quality, participant safety, and trial efficiency: Experience from a large-scale, international, randomized clinical trial
Suzanne Hartley
2017 (Liverpool) Annual Meeting
Contributed Session
Using electronic health records in clinical trials: rising to the challenge of developing a data linkage pipeline – experience from the ISCOMAT programme.
Maimoona Hashmi
2017 (Liverpool) Annual Meeting
Contributed Session
Using Electronic Healthcare Records (EHR) to screen, locate and recruit participants from primary care.
Saams Joy
2017 (Liverpool) Annual Meeting
Contributed Session
Using Graphical Displays to Monitor Start-up and Recruitment in Clinical Trials
Mirella Longo
2017 (Liverpool) Annual Meeting
Contributed Session
Using multiple qualitative methods to develop a complex intervention: the PACT study
Aleksandra Murawska
2017 (Liverpool) Annual Meeting
Contributed Session
Using Optical Character Recognition for processing paper forms in a large randomised clinical trial
Scott Evans
2017 (Liverpool) Annual Meeting
Contributed Session
Using Outcomes to Analyze Patients Rather than Patients to Analyze Outcomes: Partial Credit, Pragmatism, and Benefit:Risk Evaluation
William Stevens
2017 (Liverpool) Annual Meeting
Contributed Session
Using OWL to classify adverse events
Karen Bracken
2017 (Liverpool) Annual Meeting
Contributed Session
Using phone, SMS and email screening reminders to improve clinical trial recruitment: results from a sub-study of the T4DM Diabetes Prevention Study
Julie Bruce
2017 (Liverpool) Annual Meeting
Contributed Session
Using photographic images to aid wound assessment within a randomised controlled trial of standard wound management versus negative pressure wound therapy: UK WOLLF Trial.
Matthew Nankivell
2017 (Liverpool) Annual Meeting
Contributed Session
Using proxy responses from carers to collect quality of life data on patients with brain metastases: An analysis from the UK MRC QUARTZ trial.
Daniel Sabanés Bové
2017 (Liverpool) Annual Meeting
Educational Session
Using R for Early-Phase Dose Finding Studies
Brennan Kahan
2017 (Liverpool) Annual Meeting
Contributed Session
Using re-randomisation in clinical trials to increase patient recruitment
Jody D Ciolino
2017 (Liverpool) Annual Meeting
Educational Session
Using REDCap for Data Capture in Clinical Trials: Database Management on a Budget
Jennifer Talton
2017 (Liverpool) Annual Meeting
Contributed Session
Using REDCap’s Piping Feature to Aid in Longitudinal Data Collection
Graham Powell
2017 (Liverpool) Annual Meeting
Contributed Session
Using Routinely Recorded Data in a Clinical Trial: The Feasibility, Agreement and Additional Benefits Compared to Standard Prospective Data Collection Methods
James Glasbey
2017 (Liverpool) Annual Meeting
Contributed Session
Using trainee-led, collaborative research to generate hypotheses for multi-centre clinical trials
Ashley Hogan
2017 (Liverpool) Annual Meeting
Contributed Session
Utilizing Remote Participant Visits to Boost Retention in a Long-Term Clinical Trial
Janet Dunn
2017 (Liverpool) Annual Meeting
Contributed Session
Value of a sister observational cohort alongside a randomised controlled trial with an internal feasibility phase
Anna Heath
2017 (Liverpool) Annual Meeting
Contributed Session
Value of Sample Information as a tool in Clinical Trial Design
Leslie Carroll
2017 (Liverpool) Annual Meeting
Contributed Session
Value-Added Use of Clinical Study Data: A BioLINCC Perspective on Creating Well-Annotated Data Packages for the Wider Scientific Community
Nicola Lawrence
2017 (Liverpool) Annual Meeting
Contributed Session
Valuing the effect sizes hypothesized in phase 3 trials of targeted therapies in oncology
Erin Bengelink
2017 (Liverpool) Annual Meeting
Contributed Session
Variability in Adverse Event Reporting Rates per Subject by Enrollment Site in a Multicenter Acute Care Clinical Trial
Rachel Maishman
2017 (Liverpool) Annual Meeting
Contributed Session
Variability in composite outcomes reported in cardiac surgery studies: a literature review
Martin Adamcik
2017 (Liverpool) Annual Meeting
Contributed Session
Venous Thromboembolism and Cancer Trials Evidence Synthesis: Dealing with both Complex Knowledge and Unexplained Heterogeneity
Claudia Oblasser
2017 (Liverpool) Annual Meeting
Contributed Session
Vibrating vaginal balls to improve pelvic floor muscle performance in women after childbirth: a randomised controlled feasibility trial
Trish Hepburn
2017 (Liverpool) Annual Meeting
Contributed Session
Waiting list control designs in trials of non-pharmacological interventions for eczema
Lesley Dunleavy
2017 (Liverpool) Annual Meeting
Contributed Session
What are the barriers and facilitators to patient and carer recruitment to randomised controlled trials in palliative care? A systematic review with narrative synthesis.
Loretta Davies
2017 (Liverpool) Annual Meeting
Contributed Session
What are the methodological challenges in the design and conduct of orthopaedic randomised controlled trials comparing surgery and non-operative interventions? A systematic review
Colin Everett
2017 (Liverpool) Annual Meeting
Contributed Session
What barriers exist to statisticians recommending alternative methods to Permuted Block randomisation?
Carol Bugge
2017 (Liverpool) Annual Meeting
Contributed Session
What does qualitative case study methodology have to offer the interpretation of findings from trials of complex interventions? Reflections from a large complex intervention study.
Anna Rosala-Hallas
2017 (Liverpool) Annual Meeting
Contributed Session
What might a Global Health Trials Methodology Research Agenda look like?
Jamie Brehaut
2017 (Liverpool) Annual Meeting
Contributed Session
When Can Hypothetical Pilot Data Predict Real-World Trial Results? A Systematic Concept Review and Framework.
Anne Duncan
2017 (Liverpool) Annual Meeting
Contributed Session
When is enough, enough? Replication of behaviour change interventions to minimise attrition of follow up questionnaires
Lauren Bell
2017 (Liverpool) Annual Meeting
Contributed Session
When is the best time to internally assess recruitment in a Cluster Randomised Controlled Trial?
Seonaidh Cotton
2017 (Liverpool) Annual Meeting
Contributed Session
Why do trials get suspended? A review of data from ClinicalTrials.gov and ISRCTN
Karl Wallendszus
2017 (Liverpool) Annual Meeting
Contributed Session
Why use CDISC for trials not submitted to regulators? Lessons from the experience of an academic clinical trial unit
Claire Snowdon
2017 (Liverpool) Annual Meeting
Contributed Session
Working with a vulnerable population on a sensitive topic to better understand neonatal intensive care trials: development of a suite of strategies to meet challenges for qualitative data collection in the BRACELET Study
Junhua Zhang
2017 (Liverpool) Annual Meeting
Invited Session
Workshop for Chinese Medicine Clinical Trials