SCT Annual Meeting Presentations & Videos

Discover SCT's Scientific Knowledge-Bank

  265 Learning Opportunities Found

Mahesh Parmar
2018 (Portland) Annual Meeting
Trial of the Year Award
The Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy (STAMPEDE, NCT00268476)
Fan-fan Yu, Kathleen Reape
2018 (Portland) Annual Meeting
Trial of the Year Award
Efficacy and Safety of Voretigene Neparvovec (AAV2-hRPE65v2) in Patients with RPE65-mediated Inherited Retinal Dystrophy
William C. Cushman
2018 (Portland) Annual Meeting
Founders Lecture
Major VA and NHLBI Clinical Trials That Impacted the Management of Hypertension
Susan Halabi
2018 (Portland) Annual Meeting
Fellows Presentation
Presentation of the Class of 2018 Fellows
James J. Dignam
2018 (Portland) Annual Meeting
Award Presentation
Thomas C. Chalmers Scholarship and Sylvan Green Awards
Steven Goodman
2018 (Portland) Annual Meeting
Curtis Meinert Lecture
Research reproducibility and research reform: lessons from clinical trials
Ted Karrison, PhD
2018 (Portland) Annual Meeting
Presidential Welcome
Welcome - 2017-18 SCT President
Nicola Mills
2018 (Portland) Annual Meeting
Invited Session
Achieving the impossible? Case studies of successful recruitment to randomised clinical trials considered contentious or impossible
Theodore Lystig
2018 (Portland) Annual Meeting
Invited Session
Dynamic determination of a power prior parameter – the discount prior approach
Roger J. Lewis
2018 (Portland) Annual Meeting
Invited Session
Design of an Adaptive Trial of Extra-Corporeal Membrane Oxygenation for Refractory Out-of-hospital Cardiac Arrest (EROCA)
Lehana Thabane
2018 (Portland) Annual Meeting
Invited Session
In memory of Dave Sackett: Interim data sharing by data safety monitoring boards of trials (Alternative title: Dave Sackett’s last project on interim data sharing by DSMBs of trials)
Catherine Dillon
2018 (Portland) Annual Meeting
Invited Session
Optimizing investigational drug management to enhance clinical trial operation quality
Jeremy Grimshaw
2018 (Portland) Annual Meeting
Invited Session
Developing a framework for the ethical design and conduct of pragmatic trials: consultation with the clinical trials community
Greg Ball
2018 (Portland) Annual Meeting
Invited Session
Dynamic and Interactive Collaboration between Quantitative and Clinical Scientists: Towards a Better Way of Monitoring and Evaluating Safety Data during Clinical Development
Jeremy Grimshaw
2018 (Portland) Annual Meeting
Invited Session
Introducing the new CONSORT extension for the Stepped-Wedge Cluster Randomised Trial
Professor Jeremy Grimshaw
2018 (Portland) Annual Meeting
Invited Session
Designing Trials within Implementation Laboratories
Frank Rockhold
2018 (Portland) Annual Meeting
Invited Session
Open Sharing of Clinical Trial Data
Caitlyn Meinzer
2018 (Portland) Annual Meeting
Invited Session
Adaptive Timing of Interim Analysis for Primary Efficacy Outcome
Kirsty Loudon
2018 (Portland) Annual Meeting
Contributed Session
“Treatment As Usual” as the comparator in Randomised Controlled Trials: A scoping review of the use of the term over the past five years in six international general medical trial journals.
Katie Gillies
2018 (Portland) Annual Meeting
Contributed Session
‘It’s trying to manage the work’: a qualitative evaluation of recruitment processes within a UK multicentre trial
Sharavi Peeramsetti
2018 (Portland) Annual Meeting
Contributed Session
“Essential data for Data Monitoring Committee (DMC) review – the ideal open and closed session reports”
Barry Main
2018 (Portland) Annual Meeting
Contributed Session
“Forget-me-not” – a protocol for a pilot cluster randomised trial to pilot a core information set intervention for informed consent to invasive procedures including surgery
Eric Hardter
2018 (Portland) Annual Meeting
Contributed Session
A “compound” problem: general strategies and key resources for the utilization of approved, commercially available drugs in a blinded, controlled clinical trial
Boxian Wei
2018 (Portland) Annual Meeting
Contributed Session
A Bayesian Analysis of Small n Sequential Multiple Assignment Randomized Trials (snSMARTs)
Graham Wheeler
2018 (Portland) Annual Meeting
Contributed Session
A BAYESIAN MODEL-FREE APPROACH TO COMBINATION THERAPY PHASE I TRIALS USING CENSORED TIME-TO-TOXICITY DATA
Julia Collins
2018 (Portland) Annual Meeting
Contributed Session
A Comprehensive Customizable Site Readiness Checklist for Efficient Site Activation in a Clinical Trial
Munya Dimairo
2018 (Portland) Annual Meeting
Contributed Session
A consensus-driven reporting guidance for adaptive clinical trials: an Adaptive designs CONSORT Extension (ACE)
Xiaobo Zhong
2018 (Portland) Annual Meeting
Contributed Session
A Gate-keeping Test for Selecting Adaptive Interventions under General SMART Designs
Beata Planeta
2018 (Portland) Annual Meeting
Contributed Session
A New Approach of Modeling Time in Longitudinal Studies Involving Infrequent and Unequally Spaced Measurements
Qinshu Lian
2018 (Portland) Annual Meeting
Contributed Session
A Novel Bayesian Two-stage Design with Dynamic Historical Borrowing Using a Robust Network Meta-analytic-predictive Approach
Brian Egleston
2018 (Portland) Annual Meeting
Contributed Session
A novel randomized Phase 2 trial design that constrains sample size by requiring a sufficient experimental response rate
Haiyan Zheng
2018 (Portland) Annual Meeting
Contributed Session
A robust Bayesian meta-analytic approach for borrowing information across species in phase I clinical trials
Andrew Forbes
2018 (Portland) Annual Meeting
Contributed Session
A simple relationship between power and expected confidence interval width
Katherine Fairhurst
2018 (Portland) Annual Meeting
Contributed Session
A systematic analysis of UK nationally-funded surgical pilot and feasibility study protocols from the last 10 years to inform and optimise future surgical trials.
Erik Doffagne
2018 (Portland) Annual Meeting
Contributed Session
A Targeted Approach to Medical and Safety Reviews
Karla Hemming
2018 (Portland) Annual Meeting
Educational Session
A tutorial on sample size for efficient cluster, cluster cross-over and stepped-wedge randomised trials; including introduction to a practical on-line “app”
Michael Grayling
2018 (Portland) Annual Meeting
Contributed Session
A two-stage version of Fisher’s exact test for multi-arm trials with binary outcome variables
Kelly Miller
2018 (Portland) Annual Meeting
Contributed Session
A UNIQUE COLLABORATION FOR A DATA COORDINATING CENTER
Elizabeth Colantuoni
2018 (Portland) Annual Meeting
Contributed Session
Accounting for baseline prognostic variables and patient drop-out in the analysis of longitudinal outcomes within randomized trials for Alzheimer’s Disease
Kelsey Grantham
2018 (Portland) Annual Meeting
Contributed Session
Accounting for measurement times with a non-uniform correlation structure in sample size determination for multiple-period cluster randomised trials
Keaton Somerville
2018 (Portland) Annual Meeting
Contributed Session
ACHIEVING PROJECTED DATABASE LOCK IN A MULTI-SITE STUDY - A REPORT FROM A NIDA CTN STUDY
Ajar Kochar
2018 (Portland) Annual Meeting
Contributed Session
ADAPTABLE - A Patient-Centered, Pragmatic Randomized Clinical Trial
Laura Flight
2018 (Portland) Annual Meeting
Contributed Session
Adaptive Design Clinical Trials and their Impact on the Health Economic Analysis of Healthcare Technologies - A Qualitative Study
Christopher S. Coffey
2018 (Portland) Annual Meeting
Educational Session
Adaptive Designs - Overview, Hurdles, & Examples
Ben Saville, Ph.D.
2018 (Portland) Annual Meeting
Educational Session
Adaptive Multi-arm Platform Trials
Jonathan Chipman
2018 (Portland) Annual Meeting
Contributed Session
Adaptively Monitoring Clinical Trials with Second-Generation p-values
Jiajun Wen
2018 (Portland) Annual Meeting
Contributed Session
Adverse events in 103 randomized trials on 1st line glaucoma eye drops
Stephanie Wellford
2018 (Portland) Annual Meeting
Contributed Session
All Hands on Deck for Eligibility Checks
Chen Hu
2018 (Portland) Annual Meeting
Invited Session
Alternatives to Conventional Survival Analysis Metrics for Clinical Trials
Kandi Velarde
2018 (Portland) Annual Meeting
Contributed Session
An Initiative Using Informatics to Facilitate Clinical Research Planning and Recruitment in the VA Health Care System
Jane Candlish
2018 (Portland) Annual Meeting
Contributed Session
Analysis methods for individually randomised trials with partial clustering of outcomes
Heidi Christ-Schmidt
2018 (Portland) Annual Meeting
Contributed Session
Analysis of studies when rescue therapy censors data
Joseph Rausch
2018 (Portland) Annual Meeting
Contributed Session
Analyzing treatment effects and moderators in randomized pre-post clinical trials
Jennifer Le-Rademacher
2018 (Portland) Annual Meeting
Contributed Session
Application of Multi-State Models in Cancer Clinical Trials
Jennifer Goldsack
2018 (Portland) Annual Meeting
Contributed Session
Applying Measurement Science to the Development of Technology-Derived Novel Endpoints for use in Clinical Trials
Daniele Bottigliengo
2018 (Portland) Annual Meeting
Contributed Session
Assessing the external validity of Randomized Clinical Trials: inverse probability weighting approaches on type-2 diabetes data
Hiroko Dodge
2018 (Portland) Annual Meeting
Contributed Session
Behavioral RCT using frequent social interaction to enhance cognitive reserve
Cristina Murray-Krezan
2018 (Portland) Annual Meeting
Contributed Session
BUILDING THE FOUNDATION FOR A STATISTICS AND DATA COORDINATING CENTER WITH LIMITED RESOURCES: THE HERO STUDY, A NATIONWIDE MULTICENTER RANDOMIZED HEPATITIS C TREATMENT TRIAL
Benjamin Carlisle
2018 (Portland) Annual Meeting
Contributed Session
BURDEN AND CLINICAL IMPACT OF COMBINATION THERAPY EXPLORATION FOR NEW ANTICANCER DRUGS
Adina Stoica
2018 (Portland) Annual Meeting
Contributed Session
Calculating Antiretroviral Drug Resistance: An Innovative Open-Source Tool
Rachel Weber
2018 (Portland) Annual Meeting
Contributed Session
CENTRALIZED SOURCE DOCUMENT REVIEW: AN EFFECTIVE TOOL FOR REMOTE REVIEW OF DIGITIZED PAPER SOURCE DOCUMENTS
Wendy Seiferheld
2018 (Portland) Annual Meeting
Contributed Session
Challenges and Lessons Learned from Engaging the ClinicalTrials.gov Protocol Registration and Results System (PRS): An NRG Oncology Experience
Shelly Lensing
2018 (Portland) Annual Meeting
Contributed Session
Challenges and Successes in Recruitment of HIV Infected Persons to a Cancer Prevention Study
Roberta Scherer
2018 (Portland) Annual Meeting
Contributed Session
Challenges in conducting a multi-center trial in US military hospitals
Melissa Plets
2018 (Portland) Annual Meeting
Contributed Session
Challenges in Conducting DART (S1609), a Pioneer Basket Trial for Rare Cancers in a Cooperative Group Setting
Jeannette Lee
2018 (Portland) Annual Meeting
Contributed Session
Challenges of Conducting a Clinical Trial in Youth Correctional Facilities
Andrew Waberski
2018 (Portland) Annual Meeting
Contributed Session
Challenges with Conducting a Trial of Opioid Administration during Anesthesia in Pediatric Patients Undergoing Cardiac Surgery
Kehao Zhu
2018 (Portland) Annual Meeting
Contributed Session
Characteristics and trends of industry sponsored clinical trials with a DMC – insights from ClinicalTrials.gov
Jody Ciolino
2018 (Portland) Annual Meeting
Contributed Session
Choosing a Balancing Criterion for Complex Cluster-Randomized Trials with Continuous Baseline Variables
Rui Wu
2018 (Portland) Annual Meeting
Contributed Session
Classifying No Improvement in Visual Acuity in Children with Amblyopia Using Simulations
Barbara H. Braffett
2018 (Portland) Annual Meeting
Invited Session
Clinical Studies with Long-term Follow-up: Experiences and Lessons Learned
Jidong Jia
2018 (Portland) Annual Meeting
Invited Session
Clinical Trials in China – Opportunities and Challenges for International Collaboration
Nisha Grover
2018 (Portland) Annual Meeting
Contributed Session
Collaborative Approach to Conduct User Testing by Non-technical Research Staff
GEORGE KITSARAS
2018 (Portland) Annual Meeting
Contributed Session
Collection of real-time data from participants – interactive text surveys
Walter Ambrosius
2018 (Portland) Annual Meeting
Contributed Session
Combining SAS and LaTeX for DSMB report generation: The ENRGISE Pilot Study
Katherine Guthrie
2018 (Portland) Annual Meeting
Contributed Session
Comparison of mass mailings to Facebook advertising for recruitment of midlife women with bothersome vaginal symptoms
Valerie Durkalski-Mauldin
2018 (Portland) Annual Meeting
Invited Session
Competing with RVUs: How to successfully balance clinical research and clinical practice for the academic clinical principal investigator
Taylor Swankie
2018 (Portland) Annual Meeting
Contributed Session
Conducting High-Impact, High-Quality Clinical Trials: Site Staff Training as a Component of Quality
Claire Snowdon
2018 (Portland) Annual Meeting
Contributed Session
Conducting Non-commercial Clinical Trials Internationally - Experiences of a UK based Academic Clinical Trials Unit
Andrew Forbes
2018 (Portland) Annual Meeting
Invited Session
Covariate constrained randomisation for the design of parallel and stepped wedge cluster trials
Ayon Mukherjee
2018 (Portland) Annual Meeting
Contributed Session
Covariate-Adjusted Response-Adaptive Designs for Weibull Distributed Survival Responses
Li Chen
2018 (Portland) Annual Meeting
Invited Session
Current Development of Adaptive Designs in Clinical Trials
Andrew Forbes
2018 (Portland) Annual Meeting
Contributed Session
Decomposition of the treatment effect estimator in stepped wedge trials: Understanding the horizontal and vertical contributions
Ludovic Trinquart
2018 (Portland) Annual Meeting
Contributed Session
Design Analyses of Randomized Clinical Trials Supporting FDA Cancer Drug Approvals
Amanda Farrin
2018 (Portland) Annual Meeting
Educational Session
Design and Conduct of Efficient, Innovative Pilot & Feasibility Studies for Complex Interventions
Jonathan Cook
2018 (Portland) Annual Meeting
Contributed Session
Design and optimal use of the expertise-based randomised controlled trial design
Keith Pauls
2018 (Portland) Annual Meeting
Contributed Session
Design of an Electronic cIRB Submission Module Integrated Within a Clinical Trial Management System
Isabelle Weir
2018 (Portland) Annual Meeting
Contributed Session
Design of Non-inferiority Randomized Trials Using the Difference in Restricted Mean Survival Times
Lynn Sleeper
2018 (Portland) Annual Meeting
Contributed Session
DESIGN OF THE TEAMMATE TRIAL FOR CHILDREN WITH HEART TRANSPLANT AND DEVELOPMENT OF A NOVEL EFFICIENT ENDPOINT
Lydia Foster
2018 (Portland) Annual Meeting
Contributed Session
Designing a Non-Inferiority Trial: Bayesian versus Frequentist Approach
Jan Jansen
2018 (Portland) Annual Meeting
Contributed Session
Designing efficient trials in major trauma: the case study of REBOA
Jennifer Goldsack
2018 (Portland) Annual Meeting
Contributed Session
Designing study protocols when mobile devices are used for data capture: Recommendations from the Clinical Trials Transformation Initiative
Hakim-Moulay Dehbi
2018 (Portland) Annual Meeting
Contributed Session
Designing two- or three-arm randomized phase 2 selection trials using a margin of practical equivalence
Jamie Jackson
2018 (Portland) Annual Meeting
Contributed Session
Determining Wear Time Validation Algorithms and Cutpoints: Challenges to Using Accelerometry in a Behavioral Randomized Clinical Trial of Adolescents with Congenital Heart Disease
Heather Murray
2018 (Portland) Annual Meeting
Contributed Session
Developing a Remote Statistical Monitoring Plan
Kaleab Abebe
2018 (Portland) Annual Meeting
Contributed Session
Development and implementation of a web-based SAE adjudication system.
Kerry Avery
2018 (Portland) Annual Meeting
Contributed Session
Development of a core outcome set capturing key concepts relevant to safe and efficient evaluation of innovative invasive procedures
Diane Whitham
2018 (Portland) Annual Meeting
Contributed Session
Development of a standardised set of metrics for monitoring site performance in multicentre randomised trials: a mixed methods study
Wendy Lawton
2018 (Portland) Annual Meeting
Contributed Session
Digital Strategies for Making Clinical Trials More Accessible: SWOG’s Website Redesign
Mathew Margolis
2018 (Portland) Annual Meeting
Contributed Session
Do Site Visits Improve Participant Re-Engagement In Longitudinal Clinical Research?
Clement Ma
2018 (Portland) Annual Meeting
Contributed Session
Dual-agent dose escalation methods for pediatric oncology clinical trials
Ashley Hogan
2018 (Portland) Annual Meeting
Contributed Session
DYNAMIC MANUSCRIPT DEVELOPMENT AND TRACKING OF SCIENTIFIC PRODUCTIVITY AND IMPACT
Zhibao Mi
2018 (Portland) Annual Meeting
Contributed Session
Empirical Assessment of Trial Futility in Multicenter Clinical Trials
Carol Knott
2018 (Portland) Annual Meeting
Educational Session
Engaging ‘tricky’ sites: hints and tips
Sangeetha Paramasivan
2018 (Portland) Annual Meeting
Contributed Session
Ethical aspects of clinical trials in India: a systematic review of research in the past two decades
Cory Goldstein
2018 (Portland) Annual Meeting
Contributed Session
Ethical implications for pragmatic trials involving head-to-head comparisons of usual care interventions: an ethical analysis of the MINT trial
Ralph Trane
2018 (Portland) Annual Meeting
Contributed Session
Evaluation of Diabetic Retinopathy Using the ETDRS Severity Scale – Is There A Gold Standard?
Kimberley Goldsmith
2018 (Portland) Annual Meeting
Contributed Session
Evidenced based refinement of treatments – building mechanism evaluation into clinical trials
Nicola Greenlaw
2018 (Portland) Annual Meeting
Contributed Session
Expanding on accepted wisdoms of statistical design and analysis - stratified randomized controlled trials
Katie Gillies
2018 (Portland) Annual Meeting
Contributed Session
Exploring retention in clinical trials: A meta-ethnographic synthesis of studies reporting participant reasons for drop out
Michelle Collinson
2018 (Portland) Annual Meeting
Contributed Session
EXPLORING THE HAWTHORNE EFFECT USING A BALANCED INCOMPLETE BLOCK DESIGN IN THE ASPIRE CLUSTER RANDOMISED CONTROLLED TRIALS
Zhaomian Li
2018 (Portland) Annual Meeting
Contributed Session
Exploring the Impact of the False Discovery Rate to Correct for Multiple Comparisons
Laura Lovato
2018 (Portland) Annual Meeting
Contributed Session
Exploring the potential of clinical trial data sharing: The SPRINT Challenge
Loretta Davies
2018 (Portland) Annual Meeting
Contributed Session
Exploring treatment preference in trials which compare very different interventions: a pre-trial qualitative study
Wynne Norton
2018 (Portland) Annual Meeting
Contributed Session
Extension of the PRECIS-2 tool to assist in planning trials of multi-level interventions
Mallory Hacker
2018 (Portland) Annual Meeting
Contributed Session
Feasibility of a Seven-Day Therapeutic Washout in Early Stage Parkinson’s Disease
Kaitlyn Cook
2018 (Portland) Annual Meeting
Contributed Session
Futility Assessment via the Conditional Power for Cluster-Randomized Trials with Time-to-Event Endpoints
Melissa Schultz
2018 (Portland) Annual Meeting
Contributed Session
Graphical Summaries of Trial Conduct in DMC Reports
Kristen Mason
2018 (Portland) Annual Meeting
Contributed Session
Heat Maps for Database Lock
Heidi Gardner
2018 (Portland) Annual Meeting
Contributed Session
How do trialists go about designing their recruitment strategies? A qualitative interview study with trial stakeholders
Allison Hirst, IDEAL Project Manager & Researcher
2018 (Portland) Annual Meeting
Educational Session
How to use IDEAL (Idea, Development, Exploration, Assessment and Long-term study) to improve surgical innovation research
Asha Khachane
2018 (Portland) Annual Meeting
Contributed Session
IDEAL: Framework and Recommendations for Evaluation of Surgical Innovations
Jody Ciolino
2018 (Portland) Annual Meeting
Contributed Session
Ideas in Randomization Methods for Complex Cluster-Randomized Trials
Garrick Wallstrom
2018 (Portland) Annual Meeting
Contributed Session
Identification of High-efficacy Subgroups in Clinical Trials
Rebecca Simpson
2018 (Portland) Annual Meeting
Contributed Session
Identifying subgroups of children with asthma who are at higher risk of having an unscheduled medical contact in September: A mixed methods study
Thevaa Chandereng
2018 (Portland) Annual Meeting
Contributed Session
Imbalanced
Erik Doffagne
2018 (Portland) Annual Meeting
Contributed Session
Implementing a Scalable Risk-Based Monitoring Strategy
Lauren Yesko
2018 (Portland) Annual Meeting
Contributed Session
Implementing eCRFs in an Emergency Department environment: challenges, enhancements, and lessons learned
Jeremy Wolff
2018 (Portland) Annual Meeting
Contributed Session
Implementing Standardized Assessments in EDC: Benefits and Challenges based on Experience of Integrating the PhenX Toolkit into a Clinical Trials Network
Paul Brocklehurst
2018 (Portland) Annual Meeting
Contributed Session
Improving implementation in Wales through 'The Forum': an update
Sian Cousins
2018 (Portland) Annual Meeting
Contributed Session
Improving RCTs in invasive procedures; a proposed new definition of invasive procedures
Shaun Treweek
2018 (Portland) Annual Meeting
Contributed Session
Improving the evidence base for trial process decision-making: Studies Within A Trial (SWAT) and why we should be coordinating and doing more of them
Dr. Marjorie Jenkins
2018 (Portland) Annual Meeting
Invited Session
Including Pregnant and Lactating Women in Clinical Trials: Controversies, Challenges and Opportunities
Victoria Trapani
2018 (Portland) Annual Meeting
Contributed Session
Incorporating Aging Measures in a Long-term Multicenter Observational Study: Training and Certification Procedures
Colin Begg
2018 (Portland) Annual Meeting
Invited Session
Informed Consent and Innovative Trial Designs
Allison Furey
2018 (Portland) Annual Meeting
Contributed Session
Innovative Use of Stacked Area Plots in DMC Reporting
Wenle Zhao
2018 (Portland) Annual Meeting
Contributed Session
Integrated Drug Tracking Module in EDC-CTMS for Operation Quality Assurance in a Large Multicenter Trial
Jaemyung Kim
2018 (Portland) Annual Meeting
Contributed Session
Integrating Neuroimaging Central Repository and Tracking in Clinical Trial Management System
Brian Burke
2018 (Portland) Annual Meeting
Contributed Session
Integrating New Site Coordinators in an Ongoing Long-Term Multi-Site Observational Trial
Michael Frasketi
2018 (Portland) Annual Meeting
Contributed Session
Interactive Reporting and Visualization of Standardized Clinical Data
Toshimitsu Hamasaki
2018 (Portland) Annual Meeting
Contributed Session
Interim evaluation of efficacy or futility in group-sequential trials with two time-to-event outcomes
Brett Hanscom
2018 (Portland) Annual Meeting
Contributed Session
Interim Monitoring using Adaptive, Time-Varying Non-Inferiority Margins
Katie Gillies
2018 (Portland) Annual Meeting
Contributed Session
Interventions to improve retention to clinical trials: a behavioural analysis of effective interventions.
Stephen Nash
2018 (Portland) Annual Meeting
Contributed Session
Introducing a new Stata package for sample size calculation in trials where the outcome is a rate
Jimmy Le
2018 (Portland) Annual Meeting
Contributed Session
Is intraocular pressure, a surrogate outcome, important to patients with glaucoma?
Dixie Ecklund
2018 (Portland) Annual Meeting
Invited Session
Keeping Your Eye on the Endpoints: Study Closeout Starts from the Beginning
Heather Kopetskie
2018 (Portland) Annual Meeting
Contributed Session
Leveraging Existing Databases for Clinical Trial Data
Sudha Raman
2018 (Portland) Annual Meeting
Contributed Session
Leveraging the Electronic Health Record in a Global Outcomes Trial: Design and Rationale of the HARMONY Outcomes EHR Ancillary
Gail Mallett
2018 (Portland) Annual Meeting
Contributed Session
Maternal Characteristics Associated with Consent and Reasons for Refusal in a Randomized Controlled Trial in Pregnancy
Denise Esserman
2018 (Portland) Annual Meeting
Contributed Session
MEASURING THE IMPACT OF PATIENT PREFERENCE IN CLINICAL TRIALS
Michael Frasketi
2018 (Portland) Annual Meeting
Contributed Session
Medical Image Integration with Clinical Research Systems
Virginia Howard
2018 (Portland) Annual Meeting
Contributed Session
Methods, Successes, and Lessons Learned from Centralized Cognitive Assessment in a Multicenter Clinical Trial of Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis (CREST-2)
Fang-Shu Ou
2018 (Portland) Annual Meeting
Contributed Session
Milestone prediction for time-to-event endpoint monitoring in clinical trials
Brooke Rabe
2018 (Portland) Annual Meeting
Contributed Session
Missing data imputation methods in non-inferiority trials: a simulation study
Elaine Pascoe
2018 (Portland) Annual Meeting
Contributed Session
MISSING DATA IN THE COMPONENTS OF A BINARY COMPOSITE ENDPOINT: IMPLICATIONS FOR THE COMPOSITE
Virginia Nido
2018 (Portland) Annual Meeting
Contributed Session
MOBILE TECHNOLOGY AND CLINICAL TRIALS: PATIENT PERSPECTIVES AND OPPORTUNITIES TO REDUCE THE BURDEN OF PARTICIPATION
Danni Liu
2018 (Portland) Annual Meeting
Contributed Session
Modeling Correlated Ocular Outcomes when Both Eyes from Some but Not All Participants are Enrolled
Brian Burke
2018 (Portland) Annual Meeting
Contributed Session
Monitoring and Adjudication of Comorbidities in a Multi-Center Observational Study of Youth with Type 2 Diabetes
Jennifer Gassman
2018 (Portland) Annual Meeting
Contributed Session
Monitoring and Reporting blood pressure data quality and data completeness and blood pressure treatment arm separation for the Blood Pressure in Dialysis (BID) Pilot Study
Jason McCoy
2018 (Portland) Annual Meeting
Contributed Session
Monitoring Interactive Response Technology Vendor Implemented Randomization and Dosing Systems
Anna Bowers
2018 (Portland) Annual Meeting
Contributed Session
MONITORING OF MEDICAL EVENTS AND ADJUDICATION THROUGH CUSTOMIZABLE DIGITAL WORKFLOWS IN THE DIABETES PREVENTION PROGRAM OUTCOMES STUDY (DPPOS)
Haley Hedlin
2018 (Portland) Annual Meeting
Contributed Session
Monitoring rare events during an ongoing clinical trial
Stacey Slone
2018 (Portland) Annual Meeting
Contributed Session
My Data, Your Data, Where’s the Data?
Jonathan Cook
2018 (Portland) Annual Meeting
Contributed Session
New guidance on specifying the target difference (“effect size”) for a RCT
Claire Boyle
2018 (Portland) Annual Meeting
Contributed Session
NHANES as a Comparator Cohort
Ying Yuan
2018 (Portland) Annual Meeting
Educational Session
Novel Adaptive Designs for Phase I and II Clinical Trials
Paola Berchialla
2018 (Portland) Annual Meeting
Contributed Session
Objective inference to adjust for baseline covariates in the analysis of randomized controlled trials for increasing efficiency
Daniel Benjamin
2018 (Portland) Annual Meeting
Contributed Session
On the Accuracy of Oncology Experts’ Predictions about Safety in Randomized Cancer Trials
Pamela Tenaerts
2018 (Portland) Annual Meeting
Contributed Session
One decade of impact. One vision ahead. Optimizing the power of public-private partnership: Lessons learned from the Clinical Trials Transformation Initiative
Steven Edland
2018 (Portland) Annual Meeting
Contributed Session
Optimal Composite Endpoints for Clinical Trials of Chronic Progressive Disease
J Athene Lane
2018 (Portland) Annual Meeting
Contributed Session
Optimising recruitment in clinical trials in surgery: how do surgical trainees working together achieve success?
Sian Cousins
2018 (Portland) Annual Meeting
Contributed Session
Optimising the design of placebo-controlled RCTs of invasive procedures: An analysis of published RCTs
Jay Siegel
2018 (Portland) Annual Meeting
Contributed Session
Optimizing Phase II Clinical Trials
Jennifer Goldsack
2018 (Portland) Annual Meeting
Contributed Session
Optimizing the selection of mobile devices for data capture in clinical trials: Recommendations from the Clinical Trials Transformation Initiative
Alice Biggane
2018 (Portland) Annual Meeting
Contributed Session
Participant Input in Core Outcome Set Development: Qualitative Study
Caroline Hurley
2018 (Portland) Annual Meeting
Contributed Session
Perceived barriers and facilitators to Risk Based Monitoring in academic- led clinical trials – a mixed methods study
Alexia Iasonos
2018 (Portland) Annual Meeting
Invited Session
Phase 2 Basket Trial Designs and Applications
Graham Wheeler
2018 (Portland) Annual Meeting
Contributed Session
PHASE I TRIALS OF IMMUNOTHERAPIES AND MOLECULARLY TARGETED AGENTS: WHAT DESIGNS ARE USED, AND HOW WELL ARE THEY REPORTED?
Jose Jimenez
2018 (Portland) Annual Meeting
Contributed Session
Phase I/II Bayesian adaptive design with drug combinations and time-to-event data
Jonathan Cook
2018 (Portland) Annual Meeting
Invited Session
Placebo and sham controlled trials in surgery and in other invasive procedures: lessons, ethics and design issues
RANI JAYSWAL
2018 (Portland) Annual Meeting
Contributed Session
Practical Methods for Utilization of Biomarkers to Assess Cancer Prognosis
Scott Evans
2018 (Portland) Annual Meeting
Invited Session
Pragmatic Benefit:risk Assessment in Clinical Trials: A New Paradigm Using Pairwise Comparison of Patients
Paula Darby Lipman
2018 (Portland) Annual Meeting
Contributed Session
Pragmatic trial management: Exploring evidence for trial planning milestones
Kirsty Loudon
2018 (Portland) Annual Meeting
Educational Session
Precisely how can this tool help investigators design trials to achieve practical answers to “real world” questions?
Sonia Davis Thomas
2018 (Portland) Annual Meeting
Contributed Session
Predictive modeling of outcomes in a clinical trial with missing baseline data
Heidi Gardner
2018 (Portland) Annual Meeting
Contributed Session
Presenting user-tested evidence based tools to support development of trial recruitment strategies
on behalf of Bluebelle Study Group
2018 (Portland) Annual Meeting
Contributed Session
PSYCHOMETRIC AND INITIAL CLINICAL VALIDATION OF THE BLUEBELLE WOUND HEALING QUESTIONNAIRE (WHQ): A NEW OUTCOME MEASURE FOR POST-DISCHARGE ASSESSMENT OF WOUNDS FOR SURGICAL SITE INFECTION
Elizabeth Wright
2018 (Portland) Annual Meeting
Contributed Session
Randomized Clinical Trial Abstracts Submitted to Major Medical Meetings: Do They Include Trial Registration Numbers and Conform to Consort Guidelines?
Mackenzie Dome
2018 (Portland) Annual Meeting
Contributed Session
Reach Out: Randomized Clinical Trial of Emergency Department-Initiated Hypertension Behavioral Intervention Connecting Multiple Health Systems
Yong Zang
2018 (Portland) Annual Meeting
Invited Session
Recent Developments in Umbrella, Basket and Platform Trial Designs
Karen Bracken
2018 (Portland) Annual Meeting
Contributed Session
Recruiting men aged 50-74 years to a large diabetes prevention trial: the effectiveness of traditional vs online promotional strategies
Jamie Soames
2018 (Portland) Annual Meeting
Contributed Session
Reducing unnecessary antibiotic prescribing in primary care: a point-of-care electronic intervention using electronic healthcare records (REDUCE Trial)
Shing Lee
2018 (Portland) Annual Meeting
Invited Session
Reproducible Clinical Trials
Melanie Bell
2018 (Portland) Annual Meeting
Contributed Session
Responder analysis with missing data: comparison of two imputation techniques in the context of randomized controlled trials
Clare Relton
2018 (Portland) Annual Meeting
Contributed Session
RETHINKING THE ARCHITECTURE OF PRAGMATIC TRIALS
Amber Randall
2018 (Portland) Annual Meeting
Contributed Session
Risk-based Validation in Clinical Trial Reporting: Focus on What Matters Most
Simon Day (tentative)
2018 (Portland) Annual Meeting
Invited Session
Role of Data Monitoring Committees in Complicated Trials
David Collister
2018 (Portland) Annual Meeting
Contributed Session
Run-in periods in randomized controlled trials of chronic diseases: a meta-epidemiologic study
Wayne Feng
2018 (Portland) Annual Meeting
Contributed Session
Safety and tolerability of transcranial direct current stimulation to stroke patients - A phase I current escalation study
Wei Wang
2018 (Portland) Annual Meeting
Contributed Session
Safety Assessment Committee Joins with Data Monitoring Committee - Safety Is the New Efficacy
Maria Ciarleglio
2018 (Portland) Annual Meeting
Contributed Session
Sample Size Estimation Using a Hybrid Classical and Bayesian Procedure
DANILA AZZOLINA
2018 (Portland) Annual Meeting
Contributed Session
Sample size issues for non-inferiority clinical trials with multiple primary endpoints
Jennifer Goldsack
2018 (Portland) Annual Meeting
Contributed Session
Selecting Technology Derived Novel Endpoints for Development and Inclusion in Clinical Trials
Ying Liu
2018 (Portland) Annual Meeting
Contributed Session
SEQUENTIAL MULTIPLE ASSIGNMENT RANDOMIZED TRIALS FOR COMPARING PERSONALIZED ANTIMICROBIAL STRATEGIES (SMART COMPASS)
Sarah Finlayson
2018 (Portland) Annual Meeting
Contributed Session
Should we plan for the unplanned? Managing undesirable but unavoidable protocol amendments in clinical trials.
Kaitlyn Antonelli
2018 (Portland) Annual Meeting
Contributed Session
Site Activation Processes Predictive of Enrollment Success in a Pragmatic Precision Medicine Study
Karen Innes
2018 (Portland) Annual Meeting
Contributed Session
Site Initiation Training – What can be learned from evaluating this process from multicentre trials?
Hyunsook Chin
2018 (Portland) Annual Meeting
Contributed Session
Site Investigator vs. Sponsor SAE Causality: Are they different?
Shaun Treweek
2018 (Portland) Annual Meeting
Contributed Session
Sixty-eight studies and (nearly) nothin’ on: the poor state of the recruitment intervention methodology literature and what to do about it
Marta Bofill Roig
2018 (Portland) Annual Meeting
Contributed Session
Sizing clinical trials with composite binary endpoints
Riaz Qureshi
2018 (Portland) Annual Meeting
Contributed Session
Standardized Reporting of Randomized Clinical Trials for Systematic Reviews: Systematic Review Data Repository
Rebecca Paulus
2018 (Portland) Annual Meeting
Educational Session
Statistical Graphs in SAS Using Graphics Template Language (GTL)
Abigail Baldridge
2018 (Portland) Annual Meeting
Contributed Session
StatTag for Connecting R, SAS, and Stata to Word: A Practical Approach to Reproducibility
Abigail Baldridge
2018 (Portland) Annual Meeting
Educational Session
StatTag for Connecting R, SAS, and Stata to Word: A Practical Approach to Reproducibility
Heidi Gardner
2018 (Portland) Annual Meeting
Contributed Session
Strategies to improve participant recruitment to randomised controlled trials: A systematic review of non-randomised evaluations
Adel Gomaa Ibrahim El Feky
2018 (Portland) Annual Meeting
Contributed Session
Strategies to improve participant retention to randomized controlled trials: what do non-randomized evaluations of retention strategies have to tell us?
Tsedenia Bezabeh
2018 (Portland) Annual Meeting
Contributed Session
STREAMLINING THE PROTOCOL OVERSIGHT PROGRAM FOR MAXIMUM EFFICIENCY IN THE DIABETES PREVENTION PROGRAM OUTCOMES STUDY (DPPOS)
Kimberley Goldsmith
2018 (Portland) Annual Meeting
Educational Session
Studying Treatment Mechanisms – A Whistle Stop Tour of Simple Mediation Analysis
Eileen Stock
2018 (Portland) Annual Meeting
Contributed Session
Surveillance of Serious Adverse Events in a Multisite Clinical Trial utilizing VA Healthcare Administrative Data
Anna Moseley
2018 (Portland) Annual Meeting
Contributed Session
SURVIVAL BY HISPANIC ETHNICITY AMONG CANCER PATIENTS PARTICIPATING IN SWOG CLINICAL TRIALS
Jade Fiotto
2018 (Portland) Annual Meeting
Contributed Session
Telephonic Informed Consent for Point of Care (POC) Clinical Trials
Letitia Perdue
2018 (Portland) Annual Meeting
Contributed Session
The Central IRB Experience in a Minimal Risk Observational Study
William Wood
2018 (Portland) Annual Meeting
Contributed Session
THE CHALLENGES AND OPPORTUNITIES OF MOBILE TECHNOLOGY: A QUALITATIVE EXAMINATION OF INVESTIGATORS’ EXPERIENCES AND RECOMMENDATIONS
Jonathan Gibb
2018 (Portland) Annual Meeting
Contributed Session
The Data Extract Verify File – an open source and cross platform XML file to verify data extracts
Mary Putt
2018 (Portland) Annual Meeting
Contributed Session
The Habit Formation Trial to Evaluate Behavioral Economic Interventions to Reduce the Risk of Cardiovascular Disease: Lessons Learned
Tianchen Qian
2018 (Portland) Annual Meeting
Invited Session
The Micro-Randomized Trial Design for developing adaptive mobile health interventions
Mitra Lewis
2018 (Portland) Annual Meeting
Contributed Session
The National Drug Abuse Treatment Clinical Trials Network (NDAT CTN) Strategic Planning Group on Retention: Lessons Learned and Best Practices
Nicholas Seedorff
2018 (Portland) Annual Meeting
Contributed Session
The National Institute of Neurology Disorders and Stroke Clinical Trials Methodology Course: Outcomes of Trainees after 3 Years
Yuko Palesch
2018 (Portland) Annual Meeting
Invited Session
The Role of Central IRB vs DSMB in the Decision Making Process for Premature Termination or Enrollment Suspension of a Multicenter Trial
Jessica Kasza
2018 (Portland) Annual Meeting
Contributed Session
The standard error of the treatment effect in stepped wedge trials when the within-cluster correlation structure is misspecified
Andrea Viecelli
2018 (Portland) Annual Meeting
Contributed Session
The Standardized Outcomes in Nephrology – Hemodialysis (SONG-HD) Initiative: establishing a core outcome set for trials in patients on hemodialysis
David Kerr
2018 (Portland) Annual Meeting
Contributed Session
The Ugly Truths of Today’s DMCs – and What the SDAC Can Do to Help
Nicholas Fergusson
2018 (Portland) Annual Meeting
Contributed Session
The win ratio approach in kidney transplant trials
Ales Kotalik
2018 (Portland) Annual Meeting
Contributed Session
The win ratio approach to the analysis of a composite outcome in the Multiple Risk Factor Intervention Trial
Brian Traver
2018 (Portland) Annual Meeting
Contributed Session
Time-Course Graphics for Individual Subjects In DMC Reports
David Kerr
2018 (Portland) Annual Meeting
Educational Session
Training the Next Generation of DMC Members and the Teams that Support Them
Eve Jelstrom
2018 (Portland) Annual Meeting
Contributed Session
Translating Assessments in Clinical Trials Conducted in the US
Claire Cochran
2018 (Portland) Annual Meeting
Contributed Session
Traumatic Decisions; Research Recruitment and Randomisation in an Acute Emergency Setting
Roberta Scherer
2018 (Portland) Annual Meeting
Contributed Session
Treatment adherence in the Tinnitus Retraining Therapy Trial
Lucy Beasant
2018 (Portland) Annual Meeting
Contributed Session
Treatment preference in pediatric randomised clinical trials: systematic review and qualitative synthesis
Navneet Hakhu
2018 (Portland) Annual Meeting
Contributed Session
TWO FACTORS IMPACTING FORMULATION OF DATA MONITORING COMMITTEE RECOMMENDATIONS FOR ADAPTIVE DESIGN CLINICAL TRIALS
Michael J. Grayling
2018 (Portland) Annual Meeting
Educational Session
Understanding adaptive designs through single-arm trials
Katherine Fairhurst
2018 (Portland) Annual Meeting
Contributed Session
Understanding progression from an internal pilot to a main trial: exploring views and perceptions of key stakeholders.
J athene Lane
2018 (Portland) Annual Meeting
Contributed Session
Understanding strategies and practices that influence retention in clinical trials through an interview study of trial staff in five multi-centre trials
Lesley Curtis
2018 (Portland) Annual Meeting
Contributed Session
Understanding the Clinical Trial Enterprise’s Newest Trend: Incorporating Real-World Evidence into Randomized Clinical Trials
Chin-Fu Hsiao
2018 (Portland) Annual Meeting
Contributed Session
Use of A Bayesian Approach to Incorporate Toxicity Consideration Into The Two Stage Design of Phase II Clinical Trials
Brian Perry
2018 (Portland) Annual Meeting
Contributed Session
Use of Qualitative Data Analysis Software to Facilitate a Systematic Literature Review
Patricia Morris
2018 (Portland) Annual Meeting
Contributed Session
Using a Professional Tracing Service to Locate Participants 6 Years After Study Close-out
Jennifer Goldsack
2018 (Portland) Annual Meeting
Contributed Session
Using a single, central IRB for a nationwide pragmatic clinical trial using claims data
Kathryn Jackson
2018 (Portland) Annual Meeting
Contributed Session
Using Composite Surrogate Baseline Variables in a Modified Covariate-Constrained Randomization Algorithm
Pablo Serrano
2018 (Portland) Annual Meeting
Contributed Session
USING ELECTRONIC DATABASES TO INCREASE ACCRUAL TO GASTROINTESTINAL CANCER CLINICAL TRIALS
Lin Wang
2018 (Portland) Annual Meeting
Contributed Session
Using FDA website and ClinicalTrials.gov to identify trials for network meta-analysis: A case study on first-line medications for glaucoma
Ian Wadsworth
2018 (Portland) Annual Meeting
Contributed Session
Using model-based approaches for determining optimal dosing rules in children
Ron Marks
2018 (Portland) Annual Meeting
Contributed Session
Using Phase 2 Clinical Trial Design to Enhance the Phase 3 Process
Kellee Miller
2018 (Portland) Annual Meeting
Contributed Session
Using Qualitative Data to Develop and Refine Interventions
Shaun Treweek
2018 (Portland) Annual Meeting
Educational Session
Using Studies Within a Trial (SWATs) to increase the evidence base for trial recruitment and retention decision-making
Marcus Johnson
2018 (Portland) Annual Meeting
Contributed Session
Utilization of a Paired Comparison Analysis Framework to Inform and Prioritize Decision-Making in a Highly Matrixed Clinical Research Program
Dagmar Salazar
2018 (Portland) Annual Meeting
Contributed Session
Utilizing a Robust and Comprehensive Locator Form as a Retention Tool in Clinical Trials
Daniel Goldenholz
2018 (Portland) Annual Meeting
Contributed Session
Variability adjusted time to event (VATE) method for analysis of randomized clinical trials in epilepsy and other episodic diseases
Shun Fu Lee
2018 (Portland) Annual Meeting
Contributed Session
Variations in Design of the Stepped Wedge Cluster Randomized Trial: illustration of statistical concepts using the Patient-Centered Care Transitions in Heart Failure (PACT-HF) Trial
Alan Stevenson
2018 (Portland) Annual Meeting
Contributed Session
Video Adjudication in Clinical Trials: Enabling Distribution of Expertise and Accurate Scoring
Catherine Meyers
2018 (Portland) Annual Meeting
Invited Session
What Are We Learning from Pragmatic Clinical Trials? Design, Implementation and Analytic Strategies
Isoken Odia
2018 (Portland) Annual Meeting
Contributed Session
WHAT IS THE EFFECT OF TREATMENT CROSSOVER ON AN INTENTION TO TREAT ANALYSIS IN A NON-INFERIORITY TRIAL?
merrick.zwarenstein@ices.on.ca
2018 (Portland) Annual Meeting
Invited Session
When pragmatism and reality collide: use of the PRECIS 1 and 2 tools in PCORI funded trials
Kristen Wroblewski
2018 (Portland) Annual Meeting
Contributed Session
Why Not Buckley-James? A Simulation Study