39th Annual Meeting


May 20-23, 2018


Portland, Oregon, USA

The Conference Venue

Hilton Portland & Executive Tower

Experience Hilton's best at the newly redesigned Hilton Portland Downtown, conveniently located in the heart of the city. Enjoy our fresh new look across the lobby, the guest rooms and all meeting spaces. Take a short walk to downtown's business district, exclusive tax-free shopping, authentic restaurants, exciting entertainment venues and the MAX Light rail, just one block from the hotel.

We are located in the heart of the city, 10 miles from Portland International Airport. Walk a block from our hotel to the MAX Light Rail system for easy access to nearby cities and attractions like the Portland Saturday Market, the Oregon Museum of Science and Industry, and the Portland Art Museum.

More about the venue

registration | Pricing

Registration is now open for the 39th Annual Meeting!


* Please click here to view the list of developing countries »

Conference Registration fee includes:

  • Attendance at all sessions and entrance to the exhibition area (Monday, May 21st to Wednesday, May 23rd)
  • Delegate bag and conference program
  • Tea/Coffee and lunches on the Monday 21st, Tuesday 22nd, and Wednesday 23rd

Payment of Registration Fees
Full payment must be made by credit/debit card at the time of registering. Cards accepted are VISA, Visa Debit, MasterCard, and American Express.

Entry to the conference will not be permitted unless full payment has been received. On receipt of your registration form, a confirmation email and receipt will be sent to you by the conference organizers. If you have not received this within 5 working days of registering, please contact the conference organizers by emailing sct@fernley.com

Delegate Cancellation
Notification of cancellation must be submitted by email to the conference organizers to sct@fernley.com Cancellations made on or before May 7, 2018 will be refundedless the $50 administration fee.

Cancellations made after May 7, 2018 will NOT be refunded. No Shows will NOT be refunded.

All delegates are recommended to ensure they have the correct visas and passport requirements to travel to the conference, see below for more details and guidance

By attending the meeting, members consent to being filmed and/or photographed for SCT purposes.

Non-USA participants may require a Visa to enter the USA. To check if you need a USA Visa please visit https://travel.state.gov/content/visas/en.html. Delegates may also contact the consulate/embassy in their home country for further information.

Validity of Passports
It is your responsibility to ensure that your passport is valid for travel and we recommend that you check with your local Embassy. Please note that some countries require your passport to be valid for up to 3 months from the date of return.

**Visa Applications - Letter From The Organizing Secretariat**
If you require a letter to confirm your registration please complete the online registration form and make payment. Please email sct@fernley.com to request a letter after you have registered and made payment. If your visa is declined we are only able to offer refunds in line with our cancellation terms and conditions.

Program | Preliminary

Following is this year's preliminary program including registration opening, pre-conference workshops, keynote talks,
poster sessions, Trial of the Year presentation, Fellows induction, business meeting, student scholarships and awards.
Download Preliminary Program PDF
Pre-Conference Workshops - Sunday, May 20, 2018
8:00am - 12:00pm Pre-Conference Workshop 1
Adaptive Multi-arm Platform Trials
Pre-Conference Workshop II
Design and Conduct of Efficient,Innovative Pilot & Feasibility Studies for Complex Interventions
Pre-Conference Workshop III
Understanding adaptive designsthrough phase II single-arm trials
12:00pm - 1:00pm LUNCH BREAK (lunch not included)
1:00pm - 5:00pm Pre-Conference Workshop IV
Novel Adaptive Designs for EarlyPhase Clinical Trials
Pre-ConferenceWorkshop V
How to use IDEAL (Idea, Development, Exploration, Assessment and Long-term study)to improve surgical innovation and medical device evaluation
Pre-Conference Workshop VI
A tutorial on sample size forefficient cluster, cluster cross-over and stepped-wedge randomized trials; andintroduction to an online “app”
Sunday Evening
7:00pm - 9:00pm
Pre-conferenceWorkshop V11
Adaptive Designs: How Can We Achieve the

Pre-Conference Workshop VIII
Studying Treatment Mechanisms - A Whistle Stop Tour of Simple Mediation Analysis
Pre-ConferenceWorkshop IX
Training the Next Generation of DMC Membersand the Teams that Support Them
7:00pm - 10:00pm FELLOWS DINNER
SCT Annual Meeting - Monday, May 21, 2018
7:30am - 8:00am Coffee/Tea Break
8:00am - 12:00pm Welcome - SCT President

Curtis Meinert Keynote
Steve Goodman, MD, MHS, PhD.
Associate Dean of Clinical and Translational Research and
Professor of Medicine and of Health Research &Policy, Standford
9:30am - 10:00am BREAK (continental breakfast): Exhibits/Posters
10:00am - 11:30am Invited Session 1
Ashley Walton

Predrag Klasnja
Inbal Nahum-Shani
Mash Rabbi
Niranjan Bidargaddo

The Micro-Randomized Trial Design for developing adaptive mobile health interventions
Invited Session 2
Yuko Palesch


Yuko Palesch
Wenle Zhao
Christopher Coffey
Michael Hill

Adaptive Timing of Interim Analysis for Primary Efficacy Outcome
Invited Session 3
Dixie Ecklund


Eric Foster
Catherine Dillon
Trevis Huff
Julie Qidwai
Marianne Kearney Chase

Keeping Your Eye on the Endpoints: Study Closeout Starts from the Beginning
Invited Session 4
Spencer Hey

Lindsay Renfro,
Spencer Hey,
Monica Taljaard,
Charles Weijer

Informed Consent and Innovative Trial Designs
Invited Session 5
Marc Buyse

Frank Rockhold
Ena Bromley
Marc Buyse
Brian Bot

Pragmatic Benefit:risk Asessment in Clinical Trials: A New Paradigm Using Pairwise Comparison of Patients
In-Conference Workshop 1

StatTag for Connecting R, SAS, and Stata to Word: A Practical Approach to Reproducibility
11:30am - 12:45pm LUNCH BREAK
12:45pm - 2:15pm Invited Session 6
Rebecca Walwyn

Jeremy Grimshaw
Monica Taljaard
Shawna N. Smith
James Wason
Amanda Farrin

Designing Trials within Implementation Laboratories
Invited Session 7
Elizabeth L Turner


Elizabeth L. Turner
Andrew Copas
Fan Li
Karla Hemming

Covariate constrained randomization for the design of parallel and stepped wedge cluster trials
Invited Session 8
Ionut Bebu


Barbara H. Braffett
Ian Ford
Janet Tate
Ionut Bebu
John M. Lachin

Clinical Studies with Long-term Follow-up: Experiences and Lessons Learned
Invited Session 9 - (E,IC)
Monica Taljaard

Charles Weijer
Spencer Hey
Sarah Edwards
Monica Taljaard
Dean Fergusson

Developing a framework for the ethical design and conduct of pragmatic trials: consultation with the clinical trials community
Invited Session 10 - (DM)
Sharon Yeatts

Sharon Yeatts
Michael Linke
Michael Parides
Susan Ellenberg
Robert Silbergleit
Michele Russell-Einhorn

The Role of Central IRB vs DSMB in the Decision Making Process for Premature Termination or Enrollment Suspension of a Multicenter Trial
In-Conference Workshop 2

Engaging ‘tricky’ sites: hints and tips
2:15pm - 2:30pm BREAK (beverages only)
2:30pm-3:30pm Contributed Session 1 Contributed Session 2 Contributed Session 3 Contributed Session 4 Contributed Session 5
Contributed Session 6

3:30pm-4:00pm Break with beverages & light snack: Exhibitors/Posters
4:00pm-5:30pm Invited Session 11
Ying Yuan

Jun Yin
Jack Lee
Ying Yuan

Recent Developments in Umbrella, Basket and Platform Trial Designs
Invited Session 12
Catherine Meyers


Jason Gerson
Ryan Ferguson
Robin Boineau
Lynn DeBar
Patrick Heagerty

What Are We Learning from Pragmatic Clinical Trials?  Design, Implementation and Analytic Strategies
Invited Session 13
Karla Hemming


Karla Hemming
Monica Taljaard
Michael Grayling

Introducing the new CONSORT extension for the Stepped-Wedge Cluster Randomised Trial
Invited Session 14
Valerie Durkalski-Mauldin

Holly Hinson
Will Meurer
Pooja Khatri
Ed Jauch
Irene Ewing
Valerie Durkalski-Mauldin

Competing with RVUs: How to successfully balance clinical research and clinical practice for the academic clinical principal investigator
Invited Session 15
Greg Ball

Barbara Hendrickson
Greg Ball
Janet Wittes

Dynamic and Interactive Collaboration between Quantitative and Clinical Scientists: Towards a Better Way of Monitoring and Evaluating Safety Data during Clinical Development
Chalmers Student
Scholarship Winners

6:00pm-8:00pm RECEPTION
SCT Annual Meeting - Tuesday, May 22, 2018
7:30am - 8:00am Coffee/Tea Break
8:00am - 9:00am Presentation of the Class of 2017 Fellows

Founders Lecture
William C. Cushman, MD
Professor of Preventive Medicine and Medicine at the University of Tennessee College of Medicine,
Chief, Preventive Medicine Section, at the Veterans Affairs (VA) Medical Center in Memphis
9:00am - 9:15am BREAK
9:15am - 10:15am Contributed Session 7 Contributed Session 8 Contributed Session 9 Contributed Session 10 Contributed Session 11 Contributed Session 12
10:15am - 10:45am BREAK: (Continental Breakfast) Exhibits/Posters
10:45am - 11:45am Contributed Session 13 Contributed Session 14 Contributed Session 15 Contributed Session 16 Contributed Session 17 Contributed Session 18
11:45am - 1:15pm Lunch/SCT Business Meeting
1:15pm - 2:45pm Invited Session 16
Li Chen

Li Chen
Eva Miller
Frank Fan
Nicole (Xiaoyun) Li
Roger Lewis

Current Development of Adaptive Designs in Clinical Trials
Invited Session 17 - (TD,SA)
Chen Hu


Richard Chappell
James Dignam
Masha Kocherginsky
Chen Hu

Alternatives to Conventional Survival Analysis Metrics for Clinical Trials
Invited Session 18 - (TM,C)
Catherine Dillon


Wenle Zhao
Keith Pauls
Caitlyn Meinzer
Catherine Dillon

Optimizing investigational drug management to enhance clinical trial operation quality
Invited Session 19
Pamela Scott

Marjorie Jenkins
Karim Calis
Kevin Prohaska
Christina Bucci-Rechtweg
Anne Lyerly

Pragmatic Benefit:risk Assessment in Clinical Trials: A New Paradigm Using Pairwise Comparison of Patients
Invited Session 20
Lehana Thabane

Tom Fleming
Janet Wittes
Victoria Borg Debono

In memory of Dave Sackett: Interim data sharing by data safety monitoring boards of trials (Alternative title: Dave Sackett’s last project on interim data sharing by DSMBs of trials)
In-Conference Workshop 3

Statistical Graphs in SAS Using Graphics Template Language (GTL)
2:45pm - 3:15pm Break: Exhibits/Posters (beverage with light snack)
3:15pm - 4:45pm Invited Session 21 - (ITD)
Juliana Tolles

Will Meurer
Juliana Tolles
Dixie Ecklund
Leslie McClure

Design of an Adaptive Trial of Extra-Corporeal Membrane Oxygenation for Refractory Out-of-hospital Cardiac Arrest (EROCA)
Invited Session 22 - (TD,SA)
Theodore Lystig


Dawn Bardot
Laura Thompson
Tarek Haddad
Jason Connor

Dynamic determination of a power prior parameter – the discount prior approach
Invited Session 23 - (R)
Nicola Mills


Nicole Mills
Jenny Donovan
Jane Blazeby
David Beard

Achieving the impossible? Case studies of successful recruitment to randomised clinical trials considered contentious or impossible
Invited Session 24 - (PT)
Merrick Zwarenstein

Merrick Zwarenstein
Anne Trontell
Kirsty Loudon
Shaun Treweek
Sean Tunis

When pragmatism and reality collide: use of the PRECIS 1 and 2 tools in PCORI funded trials
Invited Session 25 - (DM)
Susan Halabi

Barry Davis, M.D., Ph.D.
Garnet Anderson, Ph.D.
Susan Halabi, Ph.D.
Oliver Sartor, M.D.

Role of Data Monitoring Committees in Complicated Trials
In-Conference Workshop 4

Using Studies within a Trial (SWATs) to increase the evidence base for trial recruitment and retention decision-making
SCT Annual Meeting - Wednesday, May 23, 2018
7:30am - 8:00am Coffee/Tea Break
8:00am - 9:00am Trial of the Year
9:00am - 9:30am BREAK (Continental Breakfast)
9:30am - 10:30am Contributed Session 19 Contributed Session 20 Contributed Session 21 Contributed Session 22 Contributed Session 23 Contributed Session 24
10:30am - 10:45am BREAK
10:45am - 12:15pm Invited Session 26 - (ITD)
Mithat Gonen

Lindsay Renfro
Kristen Cunanan
Brian Hobbs
Rong Liu

Phase 2 Basket Trial Designs and Applications
Invited Session 27 - (TD,SA)
Scott Evans


Marc Buyse
Julien Peron
Dean Follmann
Scott Evans

Pragmatic Benefit: Risk Assessment in Clinical Trials: A New Paradigm Using Pairwise Comparison of Patients
Invited Session 28 - (Other)
Yuanyuan Kong


Chen Yao
Hong You
Yuanyuan Kong
Valerie Durkalski-Mauldin

Clinical Trials in China – Opportunities and Challenges for International Collaboration
Invited Session 29 - (E,IC)
David Beard

Marion Campbell
Charles Weijer
David Beard
Jane Blazeby
Jonathan Cook

Placebo and sham controlled trials in surgery and in other invasive procedures: lessons, ethics and design issues
Invited Session 30 - (DS,R)
Denise Esserman

Michael Kane
Prasad Patil
Denise Esserman
Tze L Lai

Reproducible Clinical Trials
In-Conference Workshop 5

PRECIS-2: Precisely how can this tool help investigators design trials to achieve practical answers to “real world” questions?

About | Us

About the Annual Meeting
The Annual Meeting of the Society for Clinical Trials is a multidisciplinary program with broad participation. The Meeting brings together the clinical trials community from academia, the pharmaceutical and device industries, government agencies, medical groups and centers and clinical research entities.

Educational Highlights include:

  • Plenary sessions, simultaneous workshops and contributed presentations in presentations and posters
  • Pre-meeting workshop courses by leaders in the field
  • Annual Student Scholarship Competition
  • Exhibits from vendors showcasing publications, technology and other resources for clinical trials
  • Discussions of timely issues and research experiences among colleagues in the field of clinical trials
  • National/International travel opportunities
  • Presentation of the 2017 Trial of the Year Award
  • Presentation of the SCT Class of 2018 Fellows

This year's meeting will be held in Portland, OR “The City of Roses”. Portland boasts a world-class symphony, ballet and opera, as well as several theater groups and jazz clubs. It is also the home of the Portland Trailblazers (NBA) and the National Champion Portland Timbers (soccer).

We look forward to welcoming you to the Hilton Portland & Executive Tower, providing the perfect forum to host over 500 clinical trials colleagues, located in the heart of the city near fabulous restaurants and shopping.

The program is being developed by the SCT Program and & Education Committees, and promises to make the best of this unique opportunity for international collaboration.

We look forward to welcoming you to Portland!

About the Society
The Society for Clinical Trials (SCT) is an educational, charitable, and scientific organization whose mission is to work internationally to advance human health through advocating the use of clinical trials, leading the development and dissemination of optimal methods and practices in clinical trials, and educating and developing all clinical trial professionals. We are a society with representation from academia, industry, government and non-profit research and advocacy groups. Our community consists of clinical investigators, biostatisticians, project managers, IT specialists, clinical research associates and people from other clinical trials specialties. Our membership spans the globe with representation from 34 different countries.

Find out more: http://www.sctweb.org/

Abstract | Submissions

Please select from the five different intake systems below to submit your proposals or nominations for this year's meeting in Portland, Oregon.
All intake systems will be opened for submissions on September 5th, and will close at 11:59pm EST on the dates noted below.

Contributed Sessions

Submissions for the 2018 meeting are currently closed.

Contributed Sessions

  • Oral Presentations
  • Poster Presentations
  • Chalmers Students Scholarships
  • Sylvan Green Travel Award
Invited Sessions

Submissions for the 2018 meeting are currently closed.

Invited Sessions

  • Thematically Linked Talks
  • Invited Talks
  • Panels
  • 90 Minute Sessions
Education Sessions

Submissions for the 2018 meeting are currently closed.

Education Sessions

  • Pre-Conference Educational Workshops (4 hours)
  • In-Conference Tutorials (90 Minutes)
David Sackett Trial of the Year Award

Submissions for the 2018 meeting are currently closed.

David Sackett Trial of the Year Award

Each year the Society for Clinical Trials presents an award to a randomized clinical trial published in the previous year that best fulfills SCT predefined standards standards

Fellow of the Society for Clinical Trials

Nominations for the 2018 meeting are currently closed.

Fellow of the Society for Clinical Trials

The Society for Clinical Trials established the title of "Fellow of the Society for Clinical Trials (FSCT)" in 2005 to honor Society members who have made significant contributions to the advancement of clinical trials and to the Society.


Conference | Venue

Hotel Accommodations
The meeting will be hosted at the Hilton Portland & Executive Tower. 921 SW Sixth Avenue, Portland, Oregon 97204. Attendees can enjoy a special room rate of $219/night plus taxes. Complimentary internet in guest rooms is included in the room rate. To reserve your room online, click here. To reserve your room by phone, call 503-226-1611. Please let the hotel know that you are with SCT. Reservations must be made by April 18, 2018 in order to receive discounted rate.

Attendees who require the government per diem to reserve a room, please send an email to sct@fernley.com.

Travel Directions
From the Portland International Airport
Take I-205 SOUTH and exit onto I-84 WEST. At the end of I-84 West you will reach a junction of I-5 North and South. Go SOUTH toward Salem (to your left). Immediately follow the City Center signs to cross the Morrison Bridge. Head STRAIGHT through the traffic light near the end of the bridge onto SW Washington St, go 1 block then turn LEFT onto 3rd Ave. Take 3rd Ave 6 blocks then turn RIGHT onto SW Main St. Take Main 3 blocks and turn RIGHT onto 6th Ave, our front doors are on left.

Distance from Hotel: 10 miles
Drive Time: 30 minutes

Type Typical Minimum Charge
Limousine 50.00 USD
Super Shuttle 14.00 USD
Rental Car 40.00 USD
Subway/Rail 2.50 USD
Taxi 35.00 USD

From the North (Seattle) Southbound on I-5
Take exit 300B off of I-5 Southbound. After exiting, follow the City Center signs which will take you across the Morrison Bridge. Head STRAIGHT through the traffic light near the end of the bridge onto SW Washington St. Take Washington 1 block and then turn LEFT onto 3rd Avenue. Take 3rd Ave 6 blocks then turn RIGHT onto SW Main St. Take Main 3 blocks and turn RIGHT onto 6th Ave, our front doors are on left.

From the South (Salem) Northbound on I-5
Take the I-405 exit, EXIT 299B, on the LEFT toward CITY CENTER/US-26 W/BEAVERTON. Take EXIT 1A on the LEFT toward NAITO PKWY./JAPANESE-AMERICAN HIST. PLAZA. Stay STRAIGHT to go onto SW HARBOR DR. Turn RIGHT onto SW NAITO PKWY. Turn LEFT onto SW TAYLOR ST. Take TAYLOR 4 blocks and turn LEFT onto SW Broadway, LEFT on Salmon Street, LEFT on SW 6th Avenue, our front doors are on left hand side of 6th Avenue.

Frequently | Asked

Have a question? If you do not find the answer in our most frequently asked questions
below, please reach out to us at sct@fernley.com.

Registration will open early February 2018.
The early registration deadline is Monday, April 2, 2018 at Midnight Eastern Time.
Please see details of how to travel to the conference on the venue portion of this page.
Please click here to view the list of qualifying countries.
We request that all registrations are paid for online once the registration link is open however if this is not possible please contact us at sct@fernley.com.
All payments must be made in USD ($) to ensure that the full amount is received.
If payment is made by bank transfer we ask that you pay all bank charges. Alternatively we can accept payment by credit card where there are no additional fees unless your bank apply bank charges for international payments.
Yes. We accept Visa, MasterCard and American Express.
Receipts will be issued electronically via email. This will be the only form of receipt.
We are able to issue an invitation letter once we have received your completed registration and payment. Please make this request in the notes section at the end of the online registration process. We require a minimum of 14 days' notice and it will be sent by email. Please note that is it your responsibility to check the Visa Entry Regulations into the USA and further information can be found by clicking here.
It is your responsibility to ensure that your passport is valid for travel and we recommend that you check with your local Embassy. Please note that some countries require your passport to be valid for up to 3 months from the date of return.
Yes, our registration desk is open every day throughout the event. Please note that the on-site fees are more expensive.
It can take up to 5 days for the Conference Secretariat to process your registration and email you your confirmation and invoice. If you have not heard back from them after 5 days, please telephone (215) 320-3878 or email sct@fernley.com.
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Exhibition | Sponsors

A La Carte Sponsorships & Exhibitors

We are delighted to allow companies the ability to either sponsor or exhibit at this years conference in Portland, Oregon, USA. There are a range of opportunities available at the conference with the exhibition that will take place alongside the conference sessions and refreshment breaks.

To purchase exhibit space and a la carte sponsorships online, please click here.
For parties interested in Corporate sponsorship or paying via check, please download the prospectus and email to sct@fernley.org.

If you wish to discuss the opportunities available, we would love to answer any questions you might have.